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Epidermal Desmoglein 1 Expression Is Reduced in Kidney Transplant Recipients Compared with Immunocompetent Patients.与免疫功能正常的患者相比，肾移植受者的表皮桥粒芯糖蛋白1表达降低。
J Invest Dermatol. 2016 Sep;136(9):1908-1912. doi: 10.1016/j.jid.2016.06.001. Epub 2016 Jun 11.
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The risk of cancer in kidney transplant recipients may be reduced in those maintained on everolimus and reduced cyclosporine.在接受依维莫司和降低剂量环孢素治疗的肾移植受者中，癌症风险可能降低。
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Impact of type of calcineurin inhibitor on post-transplant tuberculosis: Single-center study from India.钙调神经磷酸酶抑制剂类型对移植后结核病的影响：来自印度的单中心研究。
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Transforming growth factor-β activated long non-coding RNA ATB plays an important role in acute rejection of renal allografts and may impacts the postoperative pharmaceutical immunosuppression therapy.转化生长因子-β激活的长链非编码RNA ATB在肾移植急性排斥反应中起重要作用，可能影响术后药物免疫抑制治疗。
Nephrology (Carlton). 2017 Oct;22(10):796-803. doi: 10.1111/nep.12851.
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Belatacept prophylaxis against organ rejection in adult kidney-transplant recipients.贝拉西普预防成人肾移植受者器官排斥反应。
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Corticosteroid-Sparing and Optimization of Mycophenolic Acid Exposure in Liver Transplant Recipients Receiving Mycophenolate Mofetil and Tacrolimus: A Randomized, Multicenter Study.接受霉酚酸酯和他克莫司的肝移植受者中皮质类固醇的减量及霉酚酸暴露的优化：一项随机、多中心研究
Transplantation. 2016 Aug;100(8):1705-13. doi: 10.1097/TP.0000000000001228.
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Safety and efficacy of the early introduction of everolimus with reduced-exposure cyclosporine a in de novo kidney recipients.在初治肾移植受者中早期引入依维莫司与低暴露量环孢素A联合使用的安全性和有效性。
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Long-term Follow-up of Kidney Transplant Recipients in the Spare-the-Nephron-Trial.肾单位 sparing 试验中肾移植受者的长期随访
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Renin-Angiotensin System Blockage and Avoiding High Doses of Calcineurin Inhibitors Prevent Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients.肾素-血管紧张素系统阻断及避免大剂量使用钙调神经磷酸酶抑制剂可预防肾移植受者的间质纤维化和肾小管萎缩。
Exp Clin Transplant. 2017 Feb;15(Suppl 1):32-36. doi: 10.6002/ect.mesot2016.O19.
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The efficacy and safety of intensified enteric-coated mycophenolate sodium with low exposure of calcineurin inhibitors in Chinese de novo kidney transplant recipients: a prospective study.在中国初发肾移植受者中，低剂量钙调神经磷酸酶抑制剂联合强化肠溶麦考酚钠的疗效与安全性：一项前瞻性研究。
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Keratinocyte cadherin desmoglein 1 controls melanocyte behavior through paracrine signaling.角蛋白细胞钙黏蛋白桥粒芯糖蛋白 1 通过旁分泌信号控制黑素细胞行为。
Pigment Cell Melanoma Res. 2020 Mar;33(2):305-317. doi: 10.1111/pcmr.12826. Epub 2019 Oct 10.

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1
Desmosomes: regulators of cellular signaling and adhesion in epidermal health and disease.桥粒：表皮健康与疾病中细胞信号传导和黏附的调节因子。
Cold Spring Harb Perspect Med. 2014 Nov 3;4(11):a015297. doi: 10.1101/cshperspect.a015297.
2
Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response.免疫抑制剂他克莫司和霉酚酸酯对角质形成细胞紫外线B反应的影响。
Photochem Photobiol. 2015 Jan-Feb;91(1):242-7. doi: 10.1111/php.12318. Epub 2014 Aug 12.
3
A network meta-analysis of the efficacy of belatacept, cyclosporine and tacrolimus for immunosuppression therapy in adult renal transplant recipients.贝拉西普、环孢素和他克莫司在成人肾移植受者免疫抑制治疗中疗效的网络荟萃分析。
Curr Med Res Opin. 2014 Aug;30(8):1473-87. doi: 10.1185/03007995.2014.898140. Epub 2014 Apr 3.
4
The desmosomal protein desmoglein 1 aids recovery of epidermal differentiation after acute UV light exposure.桥粒蛋白桥粒芯糖蛋白1有助于急性紫外线照射后表皮分化的恢复。
J Invest Dermatol. 2014 Aug;134(8):2154-2162. doi: 10.1038/jid.2014.124. Epub 2014 Mar 4.
5
Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome): part II. Prognosis, management, and future directions.原发性皮肤 T 细胞淋巴瘤（蕈样肉芽肿和赛泽里综合征）：第二部分。预后、治疗和未来方向。
J Am Acad Dermatol. 2014 Feb;70(2):223.e1-17; quiz 240-2. doi: 10.1016/j.jaad.2013.08.033.
6
Factors influencing long-term outcome after kidney transplantation.影响肾移植后长期预后的因素。
Transpl Int. 2014 Jan;27(1):19-27. doi: 10.1111/tri.12217. Epub 2013 Nov 8.
7
Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting.桥粒芯糖蛋白 1 缺乏导致严重的皮炎、多种过敏和代谢消耗。
Nat Genet. 2013 Oct;45(10):1244-1248. doi: 10.1038/ng.2739. Epub 2013 Aug 25.
8
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.桥粒芯糖蛋白 1/表皮受体酪氨酸激酶相互作用抑制 ERK 激活以支持表皮分化。
J Clin Invest. 2013 Apr;123(4):1556-70. doi: 10.1172/JCI65220. Epub 2013 Mar 25.
9
Desmoglein-1, differentiation, and disease.桥粒芯糖蛋白 1、分化和疾病。
J Clin Invest. 2013 Apr;123(4):1419-22. doi: 10.1172/JCI69071. Epub 2013 Mar 25.
10
Calcineurin signaling as a negative determinant of keratinocyte cancer stem cell potential and carcinogenesis.钙调神经磷酸酶信号作为角质形成细胞癌症干细胞潜力和癌变的负向决定因素。
Cancer Res. 2011 Mar 15;71(6):2029-33. doi: 10.1158/0008-5472.CAN-10-3750.

Epidermal Desmoglein 1 Expression Is Reduced in Kidney Transplant Recipients Compared with Immunocompetent Patients.

作者信息

Johnson Jodi L, Hoover Paul, Jovanovic Borko D, Green Kathleen J, Friedewald John J, Robinson June K

机构信息

Department of Pathology, Northwestern University, Chicago, Illinois, USA; Department of Dermatology, Northwestern University, Chicago, Illinois, USA.

Department of Dermatology, Northwestern University, Chicago, Illinois, USA.

出版信息

J Invest Dermatol. 2016 Sep;136(9):1908-1912. doi: 10.1016/j.jid.2016.06.001. Epub 2016 Jun 11.

DOI:10.1016/j.jid.2016.06.001
PMID:27302902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5044805/
Abstract
摘要