Liu Zhonghao, Jin Chengyu, Lui Raphael, Guo Rui, Yang Yongwei, Maimaitiyiming Xiaokaiti, Peng Chuanliang
Department of Orthopedics, the Second Hospital of Shandong University, Jinan, China.
Department of Thoracic Surgery, Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, China.
Indian J Surg. 2016 Apr;78(2):112-6. doi: 10.1007/s12262-015-1328-2. Epub 2015 Aug 28.
The aim of this study is to evaluate the safety and efficacy of lung volume reduction surgery (LVRS) by video-assisted thoracoscopic surgery (VATS) in the treatment of chronic obstructive pulmonary disease (COPD). A total of 90 patients with COPD from 2002 to 2012 were enrolled into our study, comprising 22 who underwent conventional thoracotomies and 68 VATS. Pulmonary function testings, arterial blood gases analysis, and quality of life between these two groups were compared. VATS was found to be superior to the conventional thoracotomy in terms of length of hospital stay, intraoperative blood loss, intubation time, volume of chest tube drainage, and postoperative pain assessment (P < 0.05). However, significant differences in pulmonary function testings, arterial blood gases analysis, 6-min walking distance (6-MWD), and postoperative quality of life between the two groups were not found (P > 0.05). LVRS by VATS is a safe and reliable surgical approach for the treatment of COPD, with less invasiveness and shorter hospital recovery time.
本研究旨在评估电视辅助胸腔镜手术(VATS)下肺减容手术(LVRS)治疗慢性阻塞性肺疾病(COPD)的安全性和有效性。2002年至2012年期间,共有90例COPD患者纳入本研究,其中22例行传统开胸手术,68例行VATS手术。比较了两组患者的肺功能测试、动脉血气分析及生活质量。结果发现,VATS在住院时间、术中失血量、插管时间、胸腔引流量及术后疼痛评估方面均优于传统开胸手术(P < 0.05)。然而,两组患者在肺功能测试、动脉血气分析、6分钟步行距离(6-MWD)及术后生活质量方面未发现显著差异(P > 0.05)。VATS下LVRS是一种安全可靠的治疗COPD的手术方法,具有创伤小、住院恢复时间短的特点。