In Seung Gyun, Han Sung Hyup, Shin Jeong Hyun, Choi Gwang Seong, Chung Moon Hyun
Department of Dermatology, Inha University College of Medicine, Incheon, Korea.
Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
Ann Dermatol. 2008 Jun;20(2):82-5. doi: 10.5021/ad.2008.20.2.82. Epub 2008 Jun 30.
Nocardiosis refers to a locally invasive or disseminated infection associated with the Nocardia species. Most infections enter through the respiratory tract and then disseminate systemically. Rarely can a primary nocardial infection of the skin spread to contiguous structures or disseminate to other internal organs in immunocompromised hosts. We describe a 70-year-old woman who suffered from recurrent nodular skin lesions on her right hand, forearm and elbow following inoculation of a traumatic injury. Analysis of the purulent exudates obtained from the nodule revealed Nocardia species. After 20 days, a chest X-ray showed newly developed multiple nodules in both lungs. The diagnosis of systemic nocardiosis was established, and we treated this case with trimethoprim-sulfamethoxazole.
诺卡菌病是指与诺卡菌属相关的局部侵袭性或播散性感染。大多数感染通过呼吸道进入,然后全身播散。在免疫功能低下的宿主中,皮肤原发性诺卡菌感染很少会扩散到相邻结构或播散到其他内脏器官。我们描述了一名70岁女性,她在手部、前臂和肘部因外伤接种后出现复发性结节性皮肤病变。对从结节中获取的脓性渗出物进行分析,发现了诺卡菌属。20天后,胸部X线显示双肺新出现多个结节。确诊为系统性诺卡菌病,我们用复方磺胺甲恶唑对该病例进行了治疗。