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锝骨扫描显示的钙过敏症:两例病例报告。

Calciphylaxis on Technetium Bone Scan: Two Case Reports.

作者信息

Gripp M J, Gagliardi J A

出版信息

Radiol Case Rep. 2015 Dec 7;2(2):30-2. doi: 10.2484/rcr.v2i2.77. eCollection 2007.

DOI:10.2484/rcr.v2i2.77
PMID:27303457
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4891618/
Abstract

Calciphylaxis is a rare but feared condition thought to related to derangements in calcium and phosphorus metabolism. The syndrome has a predilection for obese women receiving dialysis for chronic renal failure (1, 2). Patients develop painful violaceous lesions in the subcutis, which can lead to ulceration and wound-related sepsis. In severe cases, amputation is required for the gangrenous involved extremity (3). We present two cases of calciphylaxis with similar clinical presentations and physical findings.

摘要

钙过敏是一种罕见但可怕的病症,被认为与钙和磷代谢紊乱有关。该综合征多见于因慢性肾衰竭接受透析的肥胖女性(1, 2)。患者皮下会出现疼痛性紫红色病变,可导致溃疡和伤口相关的败血症。在严重情况下,受累肢体发生坏疽时需要截肢(3)。我们报告两例具有相似临床表现和体格检查结果的钙过敏病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4891618/9c0d575c0303/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4891618/6a6ae44ed041/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4891618/9bbc38db76b4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4891618/9c0d575c0303/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4891618/6a6ae44ed041/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4891618/9bbc38db76b4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4891618/9c0d575c0303/gr3.jpg

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本文引用的文献

1
Successful treatment of calciphylaxis with intravenous sodium thiosulfate.静脉注射硫代硫酸钠成功治疗钙过敏症。
Am J Kidney Dis. 2004 Jun;43(6):1104-8. doi: 10.1053/j.ajkd.2004.03.018.
2
Calciphylaxis is usually non-ulcerating: risk factors, outcome and therapy.钙过敏通常无溃疡形成:危险因素、结局及治疗
Kidney Int. 2002 Jun;61(6):2210-7. doi: 10.1046/j.1523-1755.2002.00375.x.
3
Calcified subcutaneous arterioles with infarcts of the subcutis and skin ("calciphylaxis") in chronic renal failure.慢性肾衰竭患者出现皮下小动脉钙化伴皮下组织和皮肤梗死(“钙过敏”)。
Radiol Case Rep. 2016 Dec 24;12(1):175-178. doi: 10.1016/j.radcr.2016.11.027. eCollection 2017 Mar.
Am J Kidney Dis. 2000 Apr;35(4):588-97. doi: 10.1016/s0272-6386(00)70003-5.
4
Massive necrosis of fat and skin as complication of obesity.肥胖并发症之脂肪与皮肤大面积坏死
CMAJ. 1989 Mar 15;140(6):665-8.
5
Calciphylaxis in secondary hyperparathyroidism. Diagnosis and parathyroidectomy.继发性甲状旁腺功能亢进中的钙质沉着症。诊断与甲状旁腺切除术。
Arch Surg. 1991 Oct;126(10):1213-8; discussion 1218-9. doi: 10.1001/archsurg.1991.01410340055008.