Holliday R
Bioessays. 1989 Apr;10(4):125-7. doi: 10.1002/bies.950100408.
Calorie restriction results in an increased lifespan and reduced fecundity of rodents. In a natural environment the availability of food will vary greatly. It is suggested that Darwinian fitness will be increased if animals cease breeding during periods of food deprivation and invest saved resources in maintenance of the adult body, or soma. This would increase the probability of producing viable offspring during an extended lifespan. The diversion of limited energy resources from breeding to maintenance of the soma is seen as an evolutionary adaptation, fully compatible with the 'disposable soma' theory of the evolution of ageing.
热量限制会导致啮齿动物寿命延长和繁殖力降低。在自然环境中，食物的可获得性差异很大。有人提出，如果动物在食物匮乏时期停止繁殖，并将节省下来的资源投入到成年身体（即体细胞）的维持中，达尔文适应性将会提高。这将增加在延长的寿命期间产生有活力后代的可能性。将有限的能量资源从繁殖转移到体细胞的维持被视为一种进化适应，这与衰老进化的“可抛弃体细胞”理论完全相符。
