Rockenfeller Patrick, Carmona-Gutierrez Didac, Pietrocola Federico, Kroemer Guido, Madeo Frank
Institute of Molecular Biosciences; NAWI Graz, University of Graz ; Graz, Austria.
Equipe 11 labellisée par la Ligue contre le Cancer; Centre de Recherche des Cordeliers; Paris, France; Cell Biology and Metabolomics Platforms; Gustave Roussy Comprehensive Cancer Center; Villejuif, France; INSERM; U1138; Paris, France.
Mol Cell Oncol. 2015 Mar 19;3(1):e1019023. doi: 10.1080/23723556.2015.1019023. eCollection 2016 Jan.
Ethanolamine (Etn) is a naturally occurring aminoalcohol necessary for synthesis of the phospholipid phosphatidylethanolamine (PE), a major component of biological membranes. We recently reported that Etn treatment increases cellular PE levels, thereby inducing cytoprotective autophagy and protecting against aging across species.
乙醇胺(Etn)是一种天然存在的氨基醇,是合成磷脂酰乙醇胺(PE)所必需的,而磷脂酰乙醇胺是生物膜的主要成分。我们最近报道,乙醇胺处理可提高细胞内PE水平,从而诱导具有细胞保护作用的自噬,并在不同物种中预防衰老。