研究斑马鱼幼体止血的定量方法。
Quantitative methods for studying hemostasis in zebrafish larvae.
作者信息
Rost M S, Grzegorski S J, Shavit J A
机构信息
University of Michigan, Ann Arbor, MI, United States.
出版信息
Methods Cell Biol. 2016;134:377-89. doi: 10.1016/bs.mcb.2016.01.003. Epub 2016 Feb 28.
Abstract
Hemostasis is a coordinated system through which blood is prevented from exiting a closed circulatory system. We have taken advantage of the zebrafish, an emerging model for the study of blood coagulation, and describe three techniques for quantitative analysis of primary and secondary hemostasis. Collectively, these three techniques comprise a toolset to aid in our understanding of hemostasis and pathological clotting.
摘要
止血是一个协调的系统，通过该系统可防止血液从封闭的循环系统中流出。我们利用斑马鱼这一新兴的血液凝固研究模型，描述了三种用于定量分析原发性和继发性止血的技术。这三种技术共同构成了一套有助于我们理解止血和病理性凝血的工具集。
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