Bäumer Dirk, Grant David James, Knight Ravi, Buckley Camilla, Bennett David, Rinaldi Simon
Wessex Neurological Centre, University Hospital Southampton, Southampton, UK.
Department of Neuroradiology, John Radcliffe Hospital, Oxford, UK.
Pract Neurol. 2016 Dec;16(6):488-492. doi: 10.1136/practneurol-2016-001397. Epub 2016 Jun 16.
A 71-year-old woman presented with severe back pain, limb weakness and cranial nerve dysfunction associated with high cerebrospinal fluid (CSF) protein; we diagnosed Guillain-Barré syndrome and her symptoms completely resolved after intravenous immunoglobulin. Over the next 4 years, she had three further episodes of excruciating back pain accompanied by raised CSF protein, but without weakness, sensory loss, or abnormalities in routine nerve conduction studies. Sensory evoked potentials suggested proximal demyelination and lumbosacral plexus imaging suggested inflammation. We argue that this is a relapsing proximal polyradiculoneuropathy on the spectrum of chronic inflammatory demyelinating polyradiculoneuropathy.
一名71岁女性因严重背痛、肢体无力和颅神经功能障碍就诊，脑脊液（CSF）蛋白升高；我们诊断为吉兰-巴雷综合征，静脉注射免疫球蛋白后她的症状完全缓解。在接下来的4年里，她又出现了3次剧烈背痛发作，伴有脑脊液蛋白升高，但无无力、感觉丧失或常规神经传导研究异常。感觉诱发电位提示近端脱髓鞘，腰骶丛成像提示炎症。我们认为这是慢性炎症性脱髓鞘性多发性神经根神经病谱系中的复发性近端多神经根神经病。
