与慢性不活动乙型肝炎感染相关的脱髓鞘性多发性神经病。
Demyelinating polyneuropathy associated with chronic inactive hepatitis B infection.
机构信息
King Fahad Hospital Jeddah, Jeddah, Makkah, Saudi Arabia
King Fahad Hospital Jeddah, Jeddah, Makkah, Saudi Arabia.
出版信息
BMJ Case Rep. 2021 Mar 25;14(3):e237070. doi: 10.1136/bcr-2020-237070.
Abstract
This is a case report of a 42-year-old female patient with chronic inactive hepatitis B virus (HBV) infection who presented with relapsing chronic inflammatory demyelinating polyneuropathy (CIDP). Her initial attack was of acute onset (ie, acute CIDP) resembling Guillain-Barré syndrome that responded well to intravenous immunoglobulin (IVIG) therapy. The second episode was chronic and refractory to IVIG. She was managed with plasma exchange, long-term corticosteroids, immunosuppressants and HBV antiviral therapy. She showed both clinical and electromyographic improvement, with no recurrence after 2 years of follow-up.
摘要
这是一例 42 岁女性慢性乙型肝炎病毒（HBV）感染者的病例报告，该患者患有复发性慢性炎症性脱髓鞘性多发性神经病（CIDP）。她的首次发作呈急性起病（即急性 CIDP），类似于格林-巴利综合征，对静脉注射免疫球蛋白（IVIG）治疗反应良好。第二次发作呈慢性且对 IVIG 耐药。她接受了血浆置换、长期皮质类固醇、免疫抑制剂和 HBV 抗病毒治疗。经过 2 年的随访，她的临床和肌电图均有所改善，且无复发。
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