Westerveld Donevan, Yang Dennis
Department of Internal Medicine, University of Florida College of Medicine, Gainesville, FL 32601, USA.
Division of Gastroenterology, University of Florida College of Medicine, Gainesville, FL 32601, USA.
Surg Res Pract. 2016;2016:8616581. doi: 10.1155/2016/8616581. Epub 2016 May 23.
More than one-third of the adults in the United States are obese. This complex metabolic disorder is associated with multiple comorbidities and increased all-cause mortality. Bariatric surgery has been shown to be more effective than medical therapy and has been associated with weight loss maintenance and decreased mortality. In spite of these well-established benefits, less than 1% of candidates undergo surgery due to multiple factors, such as patient and physician perceptions and attitudes, patient-physician interaction, lack of resources, and cost burden. Furthermore, even in patients who do undergo bariatric surgery and/or alternate weight loss interventions, long-term weight control is associated with high-risk failure and weight regain. In this review, we highlight some of the current barriers to bariatric surgery and long-term weight loss maintenance and underscore the importance of an individualized multidisciplinary longitudinal strategy for the treatment of obesity.
美国超过三分之一的成年人患有肥胖症。这种复杂的代谢紊乱与多种合并症以及全因死亡率增加有关。减肥手术已被证明比药物治疗更有效,并且与体重维持和死亡率降低有关。尽管有这些公认的益处,但由于多种因素,如患者和医生的认知与态度、医患互动、资源短缺和成本负担等,不到1%的候选患者接受手术。此外,即使是接受减肥手术和/或其他减肥干预措施的患者,长期体重控制也伴随着高风险失败和体重反弹。在本综述中,我们强调了减肥手术和长期体重维持目前存在的一些障碍,并强调了针对肥胖治疗采取个性化多学科纵向策略的重要性。