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体重减轻、体重反弹以及转为Roux-en-Y胃旁路手术:腹腔镜袖状胃切除术的10年结果

Weight loss, weight regain, and conversions to Roux-en-Y gastric bypass: 10-year results of laparoscopic sleeve gastrectomy.

作者信息

Felsenreich Daniel M, Langer Felix B, Kefurt Ronald, Panhofer Peter, Schermann Martin, Beckerhinn Philipp, Sperker Christoph, Prager Gerhard

机构信息

Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.

Department of Surgery, Hospital Rudolfstiftung, Vienna, Austria.

出版信息

Surg Obes Relat Dis. 2016 Nov;12(9):1655-1662. doi: 10.1016/j.soard.2016.02.021. Epub 2016 Feb 26.

Abstract

BACKGROUND

With promising short-term results, laparoscopic sleeve gastrectomy (SG) has become the second most frequently performed bariatric procedure worldwide. Aside from a growing number of reports covering up to 10 years of follow-up, only limited data have been published so far on long-term results.

OBJECTIVES

The aim of the study was to present a 10-year follow-up for SG.

SETTING

University hospital setting, Austria.

METHODS

We present the first complete 10-year follow-up of 53 consecutive patients who underwent SG before 2006. In this multicenter study, weight loss success, weight regain, and revisional surgery were analyzed beside Bariatric Analysis and Reporting Outcome System (BAROS) scores.

RESULTS

A mean maximum percent excess weight loss of 71±25% (percent total weight loss: 28±15%) was reached at a median of 12 (range 12-120) months after SG. At 10 years, a mean percent excess weight loss of 53±25% was achieved by 32 patients, corresponding to a percent total weight loss of 26.3±13.4%. Nineteen of the 53 patients (36%) were converted to Roux-en-Y gastric bypass (n = 18) or duodenal switch (n = 1) due to significant weight regain (n = 11), reflux (n = 6), or acute revision (n = 2) at a median of 36 months. Two patients died at 3 and 101 months postoperatively, unrelated to SG. A total of 31 patients (59%) suffered from weight regain of 10 kg or more, among them 24 patients (45%) with 15 kg or more, 16 patients (30%) with 20 kg or more, and 7 patients (13%) with 25 kg or more weight regain from nadir. Mean BAROS score was 2.4±2.2 at 10 years follow-up, classifying SG as "fairly efficient."

CONCLUSION

Within a long-term follow-up of 10 years or more after SG, a high incidence of both significant weight regain and intractable reflux was observed, leading to conversion, most commonly to Roux-en-Y gastric bypass.

摘要

背景

腹腔镜袖状胃切除术(SG)取得了令人满意的短期效果,已成为全球第二常见的减肥手术。除了越来越多涵盖长达10年随访的报告外,目前关于长期效果的 published 数据有限。

目的

本研究的目的是展示SG的10年随访情况。

地点

奥地利的大学医院。

方法

我们对2006年前接受SG的53例连续患者进行了首次完整的10年随访。在这项多中心研究中,除了减肥分析和报告结果系统(BAROS)评分外,还分析了体重减轻成功情况、体重反弹和翻修手术。

结果

SG术后中位时间12个月(范围12 - 120个月)时,平均最大超重减轻百分比达到71±25%(总体重减轻百分比:28±15%)。10年时,32例患者平均超重减轻百分比为53±25%,相当于总体重减轻百分比为26.3±13.4%。53例患者中有19例(36%)因体重显著反弹(n = 11)、反流(n = 6)或急性翻修(n = 2),在中位时间36个月时转为Roux-en-Y胃旁路术(n = 18)或十二指肠转位术(n = 1)。2例患者分别在术后3个月和101个月死亡,与SG无关。共有31例患者(59%)体重反弹10 kg或更多,其中24例患者(45%)体重反弹15 kg或更多;16例患者(30%)体重反弹20 kg或更多;7例患者(13%)自最低点起体重反弹25 kg或更多。10年随访时平均BAROS评分为2.4±2.2,将SG归类为“效果尚可”。

结论

在SG术后10年或更长时间的长期随访中,观察到显著体重反弹和顽固性反流的发生率较高,导致手术转换,最常见的是转为Roux-en-Y胃旁路术。

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