Sabah Salman Al, Haddad Eliana Al, Qadhi Iman, AlMuhaini Muneerah, AlAwtan Abrar, AlQabandi Omar A, AlKhayat Ali, Saleem Ammar F, Behbehani Mousa
Kuwait University, Kuwait City, Kuwait.
Jaber Al Ahmad Al Jaber Al Sabah Hospital, Kuwait City, Kuwait.
Langenbecks Arch Surg. 2025 Mar 31;410(1):112. doi: 10.1007/s00423-025-03680-1.
Despite its effectiveness, long-term data on the safety and efficacy of laparoscopic sleeve gastrectomy (LSG) for morbid obesity are sparce.
We collected data through phone interviews and hospital records for patients who had LSG, including those that then underwent revisional bariatric surgery, assessing their weight outcomes, associated health conditions, and complications.
2982 patients (72% female) were included in the study, with a maximum follow-up reached of 13 years. The mean pre-operative age and body mass index (BMI) were 34.7 ± 11.3 years and 45.5 ± 7.7 kg/m2, respectively. The prevalence of obesity classes were as follows: Class I, 3.1%; Class II, 19.2%; and Class III, 75.9%. BMI at nadir was 32.35 Kg/m2 equating to a mean nadir excess weight loss (EWL) of 67.03%. Weight outcomes at 13 years post-LSG showed a mean BMI of 31.83 kg/m and total weight loss (TWL) percentage of 31.43%. Weight loss outcomes varied according to pre-operative obesity class, with class I achieving the highest percentage EWL and class III observing the highest TWL at the end of one year. Weight regain occurred in 1.3% of the patient population, with class III experiencing the highest weight regain at 13 years. Significant reductions in comorbidities were observed, while complication rates were low, with 0.4% bleed, 0.5% leak, and 7.9% GERD.
LSG demonstrates sustained weight loss and resolution of comorbidities with low complication rates. The influence of initial obesity class on weight loss was found to be significant in the first 18 months post-LSG.
尽管腹腔镜袖状胃切除术（LSG）治疗病态肥胖症有效，但关于其安全性和有效性的长期数据却很稀少。
我们通过电话访谈和医院记录收集了接受LSG治疗的患者的数据，包括那些随后接受减重手术修正的患者，评估他们的体重结果、相关健康状况和并发症。
2982名患者（72%为女性）纳入研究，最长随访时间达13年。术前平均年龄和体重指数（BMI）分别为34.7±11.3岁和45.5±7.7kg/m²。肥胖分级的患病率如下：I级，3.1%；II级，19.2%；III级，75.9%。最低点BMI为32.35kg/m²，平均最低点超重减轻（EWL）为67.03%。LSG术后13年的体重结果显示，平均BMI为31.83kg/m，总体重减轻（TWL）百分比为31.43%。体重减轻结果因术前肥胖分级而异，I级在一年末实现了最高的EWL百分比，III级则观察到最高的TWL。1.3%的患者出现体重反弹，III级在13年时体重反弹最高。共病显著减少，并发症发生率较低，出血率为0.4%，渗漏率为0.5%，胃食管反流病（GERD）发生率为7.9%。
LSG显示出持续的体重减轻和共病的缓解，并发症发生率低。发现初始肥胖分级对LSG术后前18个月的体重减轻有显著影响。
