编码p68钙结合蛋白的基因定位于人类染色体5的q32 - q34带以及小鼠染色体11上。
The gene coding for the p68 calcium-binding protein is localised to bands q32-q34 of human chromosome 5, and to mouse chromosome 11.
作者信息
Davies A A, Moss S E, Crompton M R, Jones T A, Spurr N K, Sheer D, Kozak C, Crumpton M J
机构信息
Imperial Cancer Research Fund, London UK.
出版信息
Hum Genet. 1989 Jun;82(3):234-8. doi: 10.1007/BF00291161.
PMID:2731935
Abstract
The gene coding for human p68, a membrane-associated calcium-binding protein, has been assigned to chromosome 5, using a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids by Southern hybridisation. The gene was localised, by in situ hybridisation, to 5q32-34. The murine gene was assigned to chromosome 11, using a murine cDNA clone to probe genomic DNA from rodent-rodent somatic cell hybrids.
摘要
编码人p68（一种膜相关钙结合蛋白）的基因已被定位到5号染色体，方法是使用cDNA克隆通过Southern杂交探测啮齿动物-人类体细胞杂种的基因组DNA。通过原位杂交，该基因被定位到5q32 - 34。使用鼠cDNA克隆探测啮齿动物-啮齿动物体细胞杂种的基因组DNA，将鼠基因定位到11号染色体。
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