Kiba Keisuke, Hirayama Akihide, Yoshikawa Motokiyo, Yamamoto Yutaka, Torimoto Kazumasa, Fujimoto Kiyohide, Uemura Hirotsugu
The Department of Urology, Kinki University of Medicine, Nara Hospital.
The Department of Urology, Nara Medical University.
Hinyokika Kiyo. 2016 May;62(5):243-8.
A total of 29 men 60 years and older (mean age 74 years) who complained at least once about nocturnal voiding and were diagnosed with nocturnal polyuria in the frequency volume chart (FVC) were enrolled in this study. Body water was measured by bioelectric impedance analysis just after lying down at 4 pm and after raising legs 30 minutes later. Nocturnal urine production was measured by FVC, and urine production per unit of time at first nocturnal voiding (urine volume at first nocturnal voiding/hours of undisturbed sleep (HUS) : UFN/HUS), urine production per unit of time during sleep (total nocturnal urine volume/hours of sleep : TNV/HS), etc was evaluated. Extra cellular water (ECW) of 0.19 l (4.0%) in legs was reduced caused by body position changing. There was a significant positive correlation between the amount of ECW in legs and UFN/HUS, TNV/HS (r＝0. 57, p＝0.001 ; r＝0. 38, p＝0.042, respectively). Moreover, UFN/HUS had a significant correlation with soft lean mass in legs, ECW in legs and daytime water intake. This study suggested that a change in leg fluids caused by a change in position results in increased urine production and decreased HUS.
本研究纳入了29名60岁及以上的男性（平均年龄74岁），他们至少有一次夜间排尿问题的主诉，并且在频率-尿量图（FVC）中被诊断为夜间多尿。下午4点刚躺下时以及30分钟后抬腿后，通过生物电阻抗分析测量身体水分。通过FVC测量夜间尿量，并评估首次夜间排尿时单位时间的尿量（首次夜间排尿量/无干扰睡眠小时数（HUS）：UFN/HUS）、睡眠期间单位时间的尿量（夜间总尿量/睡眠时间：TNV/HS）等。腿部细胞外液（ECW）减少了0.19升（4.0%），这是由体位改变引起的。腿部ECW量与UFN/HUS、TNV/HS之间存在显著正相关（r分别为0.57，p = 0.001；r = 0.38，p = 0.042）。此外，UFN/HUS与腿部软瘦体重、腿部ECW和白天饮水量之间存在显著相关性。本研究表明，体位改变引起的腿部液体变化会导致尿量增加和HUS减少。
