口腔念珠菌病与糖尿病控制的关联。
Association of oral candidiasis with diabetic control.
作者信息
Hill L V, Tan M H, Pereira L H, Embil J A
机构信息
Department of Obstetrics and Gynecology, Dalhousie University, Halifax, Nova Scotia, Canada.
出版信息
J Clin Pathol. 1989 May;42(5):502-5. doi: 10.1136/jcp.42.5.502.
Abstract
Factors associated with oral candidiasis in 51 diabetics were examined. The prevalence of oral yeast infection was 49 (n = 25)%. The association with diabetic control, as measured by fasting blood glucose concentration, urinary glucose concentration, and glycosylated haemoglobin, with the presence of yeast was analysed in the 51 diabetic patients. Glycosylated haemoglobin above 12% was strongly associated with oral yeast infection (odds ratio = 13.00) (p less than 0.001), while fasting blood and urinary glucose concentrations were not. The risk of oral candidiasis among diabetics wearing dentures was significantly higher than among dentate diabetics (odds ratio = 4.78). After controlling for the effect of denture wearing, glycosylated haemoglobin greater than 12% remained highly predictive of oral yeast infection, particularly among diabetics without dentures.
摘要
对51名糖尿病患者中与口腔念珠菌病相关的因素进行了检查。口腔酵母菌感染的患病率为49%（n = 25）。在这51名糖尿病患者中，分析了通过空腹血糖浓度、尿糖浓度和糖化血红蛋白衡量的糖尿病控制情况与酵母菌存在之间的关联。糖化血红蛋白高于12%与口腔酵母菌感染密切相关（优势比 = 13.00）（p < 0.001），而空腹血糖和尿糖浓度则不然。佩戴假牙的糖尿病患者发生口腔念珠菌病的风险显著高于有牙的糖尿病患者（优势比 = 4.78）。在控制了佩戴假牙的影响后，糖化血红蛋白大于12%仍然高度预测口腔酵母菌感染，尤其是在没有佩戴假牙的糖尿病患者中。
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