蜜蜂和黄蜂毒液中具有潜在治疗应用的蛋白质和肽的活性

Activities of Venom Proteins and Peptides with Possible Therapeutic Applications from Bees and WASPS.

作者信息

Ye Xiujuan, Guan Suzhen, Liu Jiwen, Ng Charlene C W, Chan Gabriel H H, Sze Stephen C W, Zhang Kalin Y, Naude Ryno, Rolka Krzysztof, Wong Jack Ho, Ng Tzi Bun

机构信息

Key Laboratory of Biopesticide and Chemical Biology, Ministry of Education, and Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China.

Department of Social Medicine, College of Public Health, Xinjiang Medical University, Urumqi 830011, China.

出版信息

Protein Pept Lett. 2016;23(8):748-55. doi: 10.2174/0929866523666160618120824.

DOI:10.2174/0929866523666160618120824

PMID:27323949

Abstract

The variety of proteins and peptides isolated from honey bee venom and wasp venom includes melittin, adiapin, apamine, bradykinin, cardiopep, mast cell degranulating peptide, mastoparan, phospholipase A2 and secapin. Some of the activities they demonstrate may find therapeutic applications.

摘要

从蜜蜂毒液和黄蜂毒液中分离出的蛋白质和肽类包括蜂毒肽、阿迪平、蜂毒明肽、缓激肽、心脏肽、肥大细胞脱粒肽、马斯托帕兰、磷脂酶A2和secapin。它们所表现出的一些活性可能具有治疗应用价值。