三酯甘油氧化物对伤口修复效果比较的实验研究
An experimental study on the comparison of the effects of triester glycerol oxide on wound repair.
作者信息
Sezgin Serhat, Sencimen Metin, Gülses Aydin, Erdemci Fevzi, Ayna Mustafa, Gider İsmail K, Ongoru Onder, Cayci Tuncer
机构信息
Aksaz Military Hospital, Dental Service, Muğla, Turkey.
Department of Oral and Maxillofacial Surgery, Gülhane Military Medical Academy, Ankara, Turkey.
出版信息
Oral Maxillofac Surg. 2016 Sep;20(3):273-9. doi: 10.1007/s10006-016-0566-1. Epub 2016 Jun 21.
AIM
The aim of this study is to assess the effects of triester glycerol oxide (TGO) on cutaneous wound epithelization process.
MATERIAL AND METHODS
Fifty-four male Wistar rats were divided into 2 groups of 27 rats each: control(C) and TGO (PX). The groups have been divided into three subgroups which included nine rats each regarding the wound excision on the 3rd, 7th, and 10th days, respectively. The specimens were evaluated according to histological properties and hydroxyproline levels.
RESULTS
Seventh day examination showed that PX and control groups present the same score. HP levels in the control group were significantly lower compared to PX groups.
CONCLUSION
TGO have positive effects on wound epithelization process by increased collagen synthesis.
目的
本研究旨在评估三酯甘油氧化物（TGO）对皮肤伤口上皮化过程的影响。
材料与方法
54只雄性Wistar大鼠分为2组，每组27只：对照组（C）和TGO组（PX）。每组又分为三个亚组，分别在第3天、第7天和第10天进行伤口切除，每个亚组9只大鼠。根据组织学特性和羟脯氨酸水平对标本进行评估。
结果
第7天检查显示，PX组和对照组得分相同。与PX组相比，对照组的HP水平显著较低。
结论
TGO通过增加胶原蛋白合成对伤口上皮化过程有积极影响。
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