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密歇根州小儿患者用复方口服液体的标准化。

Standardization of compounded oral liquids for pediatric patients in Michigan.

机构信息

University of Michigan Health System, Ann Arbor, MI.

PACE Southeast Michigan, Detroit, MI.

出版信息

Am J Health Syst Pharm. 2016 Jul 1;73(13):981-90. doi: 10.2146/150471.

DOI:10.2146/150471
PMID:27325879
Abstract

PURPOSE

The development, dissemination, and adoption of standard concentrations for compounded oral liquids for pediatric patients in Michigan are described.

SUMMARY

A baseline assessment of current practices in Michigan revealed significant variations in the concentrations of commonly used oral liquid medicines for pediatric patients. A statewide collaborative initiative in Michigan was created to standardize the concentrations of compounded oral liquids for pediatric patients. Standard concentrations were proposed and adopted by key stakeholders. These standards were then disseminated across the state to prescribers and pharmacists, with encouragement to voluntarily adopt the standards as a patient safety measure. A follow-up survey was conducted to evaluate adoption of the standards. A total of 263 pharmacists responded to the survey. Standardization of the concentrations of compounded oral liquids in Michigan was welcomed by most pharmacies and is perceived to have reduced the risk for errors at transitions of care for children receiving compounded oral liquids. Awareness of the standardization initiative was acknowledged by 77% of survey respondents, and adoption of the standards was observed to some degree by 57% of survey respondents. In addition, 70% of survey respondents agreed or strongly agreed that adoption of the standards has improved patient safety in Michigan.

CONCLUSION

Standard drug concentrations for compounded oral liquids were developed for pediatric patients in Michigan. A survey after dissemination of the recommended standards confirmed general awareness of the initiative and adoption of the standards by a substantial proportion of respondents. Most respondents indicated a belief that creation of the standards improved patient safety.

摘要

目的

描述密歇根州为儿科患者配制的复方口服液体的标准浓度的开发、传播和采用情况。

摘要

对密歇根州当前实践情况的基线评估显示,儿科患者常用口服液体药物的浓度存在显著差异。密歇根州创建了一个全州范围的合作倡议,以标准化儿科患者配制的口服液体浓度。标准浓度由主要利益相关者提出并采用。这些标准随后在全州范围内分发给处方医生和药剂师,并鼓励他们作为患者安全措施自愿采用这些标准。进行了后续调查以评估标准的采用情况。共有 263 名药剂师对调查做出了回应。大多数药店对密歇根州口服液体的浓度标准化表示欢迎,并认为这降低了接受配制口服液体的儿童在治疗过渡期间出错的风险。77%的调查受访者承认了解标准化倡议,57%的调查受访者在一定程度上采用了这些标准。此外,70%的调查受访者同意或强烈同意采用这些标准提高了密歇根州的患者安全性。

结论

为密歇根州的儿科患者制定了复方口服液体的标准药物浓度。在推荐标准传播后的调查证实了大多数受访者对该倡议的普遍认识以及对标准的采用。大多数受访者表示相信制定这些标准提高了患者安全性。

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