Tharkar Shabana, Viswanathan Vijay
MV Hospital for Diabetes and Diabetes Research Center, WHO Collaborating Centre for Research, Education and Training in Diabetes, Royapuram, Chennai, India.
Heart Asia. 2010 Jan 1;2(1):145-9. doi: 10.1136/ha.2009.000950. eCollection 2010.
Non-communicable diseases are on the rise globally, and developing countries are also witnessing the burden. Rising obesity levels are a matter of serious concern owing to the well-established link between obesity and non-communicable diseases. The objective of this study was to determine the effect of obesity on the prevalence of cardiovascular risk factors among the Indian population.
Data on blood pressure, anthropometric and biochemical measurements were collected for 2021 subjects aged above 20 years. Measurements were restricted to only anthropometrics for those below 20 years (N=1289). The study population was categorised into three groups according to body mass index for statistical analysis.
The prevalence of overweight and obesity was 29.5% and 11.1%, respectively, which shows significant rising trends since 1995. Glucose intolerance, dyslipidaemia, hypertension and metabolic syndrome were significantly higher among the overweight and obese subjects than among normal subjects. The prevalence of metabolic syndrome was 59% among the obese group, showing the highest risk for that group. Overweight and obesity, increasing age, hypercholesterolaemia and family history of hypertension showed a strong association with metabolic syndrome.
All the cardiometabolic abnormalities showed an increasing trend with increase in body mass index. The morbidity and mortality associated with cardiovascular diseases can be reduced by curbing the obesity epidemic.
非传染性疾病在全球范围内呈上升趋势，发展中国家也面临着这一负担。肥胖水平的上升令人严重担忧，因为肥胖与非传染性疾病之间的联系已得到充分证实。本研究的目的是确定肥胖对印度人群心血管危险因素患病率的影响。
收集了2021名20岁以上受试者的血压、人体测量和生化测量数据。对于20岁以下的受试者（N = 1289），测量仅限于人体测量学。为了进行统计分析，根据体重指数将研究人群分为三组。
超重和肥胖的患病率分别为29.5%和11.1%，自1995年以来呈显著上升趋势。超重和肥胖受试者的糖耐量异常、血脂异常、高血压和代谢综合征显著高于正常受试者。肥胖组的代谢综合征患病率为59%，表明该组风险最高。超重和肥胖、年龄增长、高胆固醇血症和高血压家族史与代谢综合征密切相关。
所有心脏代谢异常均随着体重指数的增加而呈上升趋势。通过控制肥胖流行，可以降低心血管疾病相关的发病率和死亡率。
