Mohan Viswanathan, Jaydip Revale, Deepa Raj
Madras Diabetes Research Foundation & Dr Mohan's Diabetes Specialities Centre, Chennai, India.
Pediatr Diabetes. 2007 Dec;8 Suppl 9:28-34. doi: 10.1111/j.1399-5448.2007.00328.x.
The prevalence of youth-onset type 2 diabetes is increasing worldwide in parallel with the obesity epidemic. In India, the age at onset of type 2 diabetes had traditionally been a decade or two earlier compared with the western population. Hence, it is not surprising that the prevalence of youth-onset type 2 diabetes is rapidly escalating in India not only among the more affluent sections of society but also in the middle and lower socioeconomic groups as well. In India, type 2 diabetes in youth overlaps with monogenic forms of diabetes such as maturity-onset diabetes of the young, fibrocalculous pancreatic diabetes, and malnutrition-modulated diabetes, all of which are ketosis-resistant forms of youth-onset diabetes. Screening of high-risk groups may help in the early detection of youth-onset type 2 diabetes and prevention of its complications. Primary prevention would require a multisectoral approach involving the government and non-governmental agencies with a focus on healthier lifestyles among children.
青少年2型糖尿病的患病率在全球范围内随着肥胖症的流行而上升。在印度,2型糖尿病的发病年龄传统上比西方人群早一二十年。因此,青少年2型糖尿病的患病率在印度迅速上升也就不足为奇了,不仅在社会较富裕阶层中如此,在社会经济地位中等和较低的群体中也是如此。在印度,青少年2型糖尿病与单基因糖尿病形式重叠,如青年发病的成年型糖尿病、纤维钙化性胰腺糖尿病和营养不良调节性糖尿病,所有这些都是青少年发病糖尿病的抗酮症形式。对高危人群进行筛查可能有助于早期发现青少年2型糖尿病并预防其并发症。一级预防需要政府和非政府机构采取多部门方法,重点关注儿童更健康的生活方式。