Rea G, Perna F, Calabrese G, Molino A, Valente T, Vatrella A
Department of Diagnostic Imaging, Monaldi Hospital, Naples, Italy.
Respiratory Medicine Division, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Transl Med UniSa. 2016 May 16;14:64-8. eCollection 2016 May.
Lipoid pneumonia is an uncommon disorder characterized by accumulation of lipid components into the interstitial and alveolar compartment. The usual classification distinguishes endogenous and exogenous and acute or chronic forms, related to the type of fats, the amount of damage and the time of exposure. We describe a case of exogenous lipoid pneumonia by inhalation of vaseline used for cleaning of the tracheostoma in a 63-year-old female, presenting as cough, worsening dyspnea in few weeks. The diagnosis was finally established with a re-evaluation of BAL with specific staining for lipids, revealing the presence of foamy macrophages lipids rich, according to HRCT findings.
脂质性肺炎是一种罕见的疾病,其特征是脂质成分在间质和肺泡腔中蓄积。通常的分类方法可区分内源性和外源性以及急性或慢性形式,这与脂肪类型、损害程度和接触时间有关。我们描述了一例63岁女性因吸入用于清洁气管造口的凡士林而导致的外源性脂质性肺炎病例,患者表现为咳嗽,数周内呼吸困难加重。最终,根据高分辨率CT(HRCT)结果,通过对支气管肺泡灌洗(BAL)进行重新评估并采用脂质特异性染色,发现存在富含脂质的泡沫状巨噬细胞,从而确诊。