Tapaneya-Olarn W, Osatakul S, Chatasingh S, Tapaneya-Olarn C
J Med Assoc Thai. 1989 Jan;72 Suppl 1:35-8.
Fifty-six patients with acute glomerulonephritis were studied prospectively during 1984. Their ages ranged from 10 months to 14 years old with the peak age range between 5 to 9 years. Most of them had edema, hypertension, hematuria with or without proteinuria and had low serum complement. Azotemia was found in 45 per cent of the cases. Serologic evidence for streptococcal infection was positive in 68 per cent and only 6 per cent had positive culture. Edema and hypertension were all resolved within 2 weeks. All patients that were followed up had normal serum complement by the 6th week, normal BUN, Scr by one year. The hematuria disappeared by 6 months and proteinuria by 2 months in 50 per cent of the cases. By the 4th year only one patient had microscopic hematuria and mild proteinuria with normal serum creatinine, normotension and no edema. In conclusion, in Thailand AGN is still a common kidney disease in children but with prompt and proper treatment its prognosis is still very good.
1984年对56例急性肾小球肾炎患者进行了前瞻性研究。他们的年龄从10个月到14岁不等，高峰年龄在5至9岁之间。他们大多数有水肿、高血压、血尿伴或不伴蛋白尿，且血清补体水平低。45%的病例发现有氮质血症。68%的病例有链球菌感染的血清学证据，只有6%的病例培养结果呈阳性。水肿和高血压在2周内全部消退。所有接受随访的患者在第6周时血清补体正常，1年后血尿素氮、血肌酐正常。50%的病例血尿在6个月内消失，蛋白尿在2个月内消失。到第4年，只有1例患者有镜下血尿和轻度蛋白尿，血清肌酐正常，血压正常且无水肿。总之，在泰国，急性肾小球肾炎仍是儿童常见的肾脏疾病，但通过及时、恰当的治疗，其预后仍然非常好。
