米索硝唑（Ro 07-0582）的放射增敏作用。增敏剂作用时机和肿瘤浓度的重要性。 - Suppr

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超能文献

Radiosensitization by misonidazole (Ro 07-0582). The importance of timing and tumor concentration of sensitizer.

作者信息

McNally N J, Denekamp J, Sheldon P, Flockhart I R, Stewart F A

出版信息

Radiat Res. 1978 Mar;73(3):568-80.

PMID:273269

Abstract

摘要

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Radiosensitization by misonidazole (Ro 07-0582). The importance of timing and tumor concentration of sensitizer.米索硝唑（Ro 07-0582）的放射增敏作用。增敏剂作用时机和肿瘤浓度的重要性。

Radiat Res. 1978 Mar;73(3):568-80.

Cytotoxic effects of the hypoxic cell radiosensitizer Ro 7-0582 to tumor cells in vivo.缺氧细胞放射增敏剂Ro 7-0582对体内肿瘤细胞的细胞毒性作用。

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Combinations of radiation and misonidazole in a murine lung tumor model.小鼠肺癌模型中放射与米索硝唑的联合应用。

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The response of a transplantable tumor to fractionated irradiation. II. Fast neutrons.

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[Radiosensitization of C3H/He mammary carcinoma by administration of hyperthermia and/or of misonidazole (author's transl)].通过热疗和/或米索硝唑给药对C3H/He乳腺癌的放射增敏作用（作者译）

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The effect of hypoxic radiosensitizer after mild hyperthermia in C3H mammary carcinoma.轻度热疗后低氧放射增敏剂对C3H乳腺癌的影响。

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引用本文的文献

Dose-dependence and related studies on the pharmacokinetics of misonidazole and desmethylmisonidazole in mice.米索硝唑和去甲基米索硝唑在小鼠体内的药代动力学剂量依赖性及相关研究

Cancer Chemother Pharmacol. 1980;5(1):27-37. doi: 10.1007/BF00578559.

Radiosensitisers.放射增敏剂

Br Med J. 1980 Oct 25;281(6248):1089-90.

Phenytoin shortens the half-life of the hypoxic cell radiosensitizer misonidazole in man: implications for possible reduced toxicity.苯妥英钠可缩短人体中缺氧细胞放射增敏剂米索硝唑的半衰期：对可能降低毒性的意义。

Br J Cancer. 1980 Feb;41(2):302-4. doi: 10.1038/bjc.1980.43.

Effect of misonidazole and hyperthermia on the radiosensitivity of a C3H mouse mammary carcinoma and its surrounding normal tissue.米索硝唑与热疗对C3H小鼠乳腺癌及其周围正常组织放射敏感性的影响。

Br J Cancer. 1980 Jan;41(1):10-21. doi: 10.1038/bjc.1980.2.

Is tumour radiosensitization by misonidazole a general phenomenon?米索硝唑引起的肿瘤放射增敏是一种普遍现象吗？

Br J Cancer. 1980 Jan;41(1):1-9. doi: 10.1038/bjc.1980.1.

Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients.苯妥英钠对放疗患者米索硝唑药代动力学的影响。

Br J Cancer. 1981 Oct;44(4):592-6. doi: 10.1038/bjc.1981.232.

Enhancement of the effect of cytotoxic drugs by radiosensitizers.放射增敏剂增强细胞毒性药物的作用。

Br J Cancer. 1981 Jun;43(6):756-66. doi: 10.1038/bjc.1981.113.

In vivo assessment of basic 2-nitroimidazole radiosensitizers.2-硝基咪唑类基础放射增敏剂的体内评估

Br J Cancer. 1982 Jul;46(1):127-37. doi: 10.1038/bjc.1982.174.

The penetration of misonidazole into a mature structural cartilage.米索硝唑在成熟结构软骨中的渗透情况。

Br J Cancer. 1982 Feb;45(2):282-5. doi: 10.1038/bjc.1982.44.

In vivo-in vitro tumour cell lines: characteristics and limitations as models for human cancer.体内-体外肿瘤细胞系：作为人类癌症模型的特征与局限性

Br J Cancer Suppl. 1980 Apr;4:118-22.

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