Raeste A M, Aura A
Scand J Dent Res. 1978 Jan;86(1):43-51. doi: 10.1111/j.1600-0722.1978.tb00606.x.
The rate of migration of leukocytes (OMR) was estimated by counts of sequential mouthrinses in 81 human subjects in order to evaluate its usefulness as a laboratory test of oral inflammation. Periodontitis was taken as a model, and neither patients nor controls had any other oral inflammation. Patients with advanced periodontitis, but with periodontal destruction of about the same level, were divided into two groups, acute phase and chronic phase. The mean number of leukocytes entering the oral cavity in 30 s was estimated in these two groups. In the same patients the difference between the cell count in the first rinse and the OMR level was estimated, to test whether it could be taken to indicate the grade of acuteness of the inflammation (GAI). OMR and GAI were assessed in the patients with periodontitis after the initial treatment and at follow-up 1 year after completion of the full treatment, which almost always included surgical procedures. The results indicate that the OMR reflects the existence of oral inflammation and can be used as a laboratory test with the same reservations as white blood cell counts for systemic inflammation. The difference in GAI between patients in the acute and chronic phases of the disease was highly significant, indicating that this test gives information about the severity of the inflammation.
为评估白细胞迁移率（OMR）作为口腔炎症实验室检测指标的效用，对81名人类受试者进行了连续漱口计数以估算该指标。以牙周炎为模型，患者和对照组均无其他口腔炎症。患有晚期牙周炎但牙周破坏程度大致相同的患者被分为两组，即急性期和慢性期。估算了这两组患者在30秒内进入口腔的白细胞平均数。在同一批患者中，估算了首次漱口时的细胞计数与OMR水平之间的差异，以检验其是否可用于指示炎症的急性程度分级（GAI）。在牙周炎患者接受初始治疗后以及在完成几乎总是包括外科手术的全面治疗1年后的随访中，对OMR和GAI进行了评估。结果表明，OMR反映了口腔炎症的存在，并且可以作为一种实验室检测指标，与用于全身性炎症的白细胞计数具有相同的局限性。疾病急性期和慢性期患者的GAI差异非常显著，表明该检测可提供有关炎症严重程度的信息。
