Yu Lifeng, Leng Shuai, McCollough Cynthia H
Department of Radiology, Mayo Clinic, Rochester, MN.
Proc SPIE Int Soc Opt Eng. 2016 Feb;9783. doi: 10.1117/12.2217446. Epub 2016 Mar 22.
Energy-resolved photon-counting CT (PCCT) is promising for material decomposition with multi-contrast agents. However, corrections for non-idealities of PCCT detectors are required, which are still active research areas. In addition, PCCT is associated with very high cost due to lack of mass production. In this work, we proposed an alternative approach to performing multi-energy CT, which was achieved by acquiring triple or quadruple x-ray beam measurements on a dual-source CT scanner. This strategy was based on a "Twin Beam" design on a single-source scanner for dual-energy CT. Examples of beam filters and spectra for triple and quadruple x-ray beam were provided. Computer simulation studies were performed to evaluate the accuracy of material decomposition for multi-contrast mixtures using a tri-beam configuration. The proposed strategy can be readily implemented on a dual-source scanner, which may allow material decomposition of multi-contrast agents to be performed on clinical CT scanners with energy-integrating detector.
能量分辨光子计数CT(PCCT)在使用多种造影剂进行物质分解方面很有前景。然而,需要对PCCT探测器的非理想性进行校正,这仍是活跃的研究领域。此外,由于缺乏大规模生产,PCCT成本非常高。在这项工作中,我们提出了一种执行多能量CT的替代方法,该方法通过在双源CT扫描仪上获取三重或四重X射线束测量来实现。该策略基于单源扫描仪上用于双能量CT的“双束”设计。提供了三重和四重X射线束的光束滤波器和光谱示例。进行了计算机模拟研究,以评估使用三束配置对多对比混合物进行物质分解的准确性。所提出的策略可以很容易地在双源扫描仪上实现,这可能允许在具有能量积分探测器的临床CT扫描仪上对多种造影剂进行物质分解。