Kelly E L, Neser W, Francis R
J Natl Med Assoc. 1989 Feb;81(2):143-52.
Few controlled studies on the clinical course of hypertension in the elderly have been done, and similar studies are lacking specifically regarding the aging black population. Such studies are indeed difficult considering the complexity of determining the true incidence and prevalence of the disease, the presence of confounding variables such as genetic and environmental influences, and physiologic effects of aging. However, United States vital statistics data on race- and age-specific mortality and morbidity from cardiovascular and cerebrovascular disease are available. The literature has established that hypertension is the principal risk factor and has a direct relationship to the evolution of cardio- and cerebrovascular events. Therefore, examination of these data together with hypertension morbidity could contribute to our knowledge of the prevalence of hypertension in the elderly black population.
针对老年人高血压临床病程的对照研究很少,尤其缺乏针对老年黑人人群的类似研究。考虑到确定该疾病的真实发病率和患病率的复杂性、诸如遗传和环境影响等混杂变量的存在以及衰老的生理影响,此类研究确实困难。然而,美国有按种族和年龄划分的心血管和脑血管疾病死亡率及发病率的生命统计数据。文献表明,高血压是主要风险因素,与心血管和脑血管事件的发展有直接关系。因此,将这些数据与高血压发病率一起进行研究,有助于我们了解老年黑人人群中高血压的患病率。