Shi Rong-Liang, Qu Ning, Gao Li-Li, Lu Zhong-Wu, Sun Guo-Hua, Ji Qing-Hai
Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China; Department of General Surgery, Minhang Hospital, Fudan University, Shanghai 201199, P.R. China.
Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Biomed Rep. 2016 Jul;5(1):79-82. doi: 10.3892/br.2016.670. Epub 2016 May 4.
The primary occurrence of synovial sarcoma (SS) in the thyroid is quite rare. As other SS arise from the head and neck structure, it tends to present poor biological behaviors and is generally treated as a high-grade sarcoma. The present study reports the case of a 31-year-old male who presented a neck mass, involving the thyroid, as shown by ultrasonography. The tumor was resected by total thyroidectomy and diagnosed as SS by histopathology. However, the initial surgery was considered as incomplete (R2) and no adjuvant protocol was followed. At the follow-up, neck recurrences within local lymph nodes were found repeatedly. The tumor grade increased for the metastatic lesions, indicating poorer differentiations with repeated relapses. The accurate evaluations of the primary tumor facilitated it to tailor the initial treatments, otherwise, the prognosis may be deteriorated by inappropriate management.
甲状腺原发性滑膜肉瘤（SS）极为罕见。与其他起源于头颈部结构的SS一样，它往往表现出不良的生物学行为，通常被视为高级别肉瘤。本研究报告了一例31岁男性病例，该患者出现颈部肿块，超声检查显示肿块累及甲状腺。通过全甲状腺切除术切除肿瘤，经组织病理学诊断为SS。然而，最初的手术被认为是不完全切除（R2），且未遵循辅助治疗方案。在随访中，局部淋巴结反复出现颈部复发。转移灶的肿瘤分级升高，表明随着复发次数增加，分化程度更差。对原发性肿瘤的准确评估有助于制定初始治疗方案，否则，不恰当的处理可能会使预后恶化。
