Great Ormond Street Hospital for Children NHS Trust, Department of Radiology, London, UK.
National Hospital for Neurology and Neurosurgery, Department of Radiology, London, UK.
Childs Nerv Syst. 2022 Jan;38(1):33-50. doi: 10.1007/s00381-021-05359-6. Epub 2021 Sep 16.
Pineal, sellar and suprasellar tumours in children comprise a wide range of diseases with different biological behaviours and clinical management. Neuroimaging plays a critical role in the diagnosis, treatment planning and follow up of these patients, but imaging interpretation can prove challenging due to the significant overlap in radiological features.
A review of the literature was performed by undertaking a search of the MEDLINE and EMBASE databases for appropriate MeSH terminology. Identified abstracts were screened for inclusion and articles meeting the objectives of the review were included.
In this article, we review radiological appearances of common and uncommon pineal, sellar and suprasellar tumours occurring in the paediatric population. We discuss the importance of anatomical localization, clinical information and cerebrospinal fluid tumour markers, and propose a practical approach to differential diagnosis. Lastly, we discuss future directions and prospective new imaging strategies to support state-of-the-art patient care.
儿童松果体、鞍区和鞍上肿瘤包含一系列具有不同生物学行为和临床管理方式的疾病。神经影像学在这些患者的诊断、治疗计划和随访中起着至关重要的作用，但由于影像学特征有很大的重叠，影像学解读可能具有挑战性。
通过对 MEDLINE 和 EMBASE 数据库进行检索，使用适当的 MeSH 术语进行文献回顾。筛选出纳入的摘要，并纳入符合综述目的的文章。
在本文中，我们回顾了在儿童中常见和不常见的松果体、鞍区和鞍上肿瘤的影像学表现。我们讨论了解剖定位、临床信息和脑脊液肿瘤标志物的重要性，并提出了一种实用的鉴别诊断方法。最后，我们讨论了未来的方向和有前景的新成像策略，以支持最先进的患者治疗。
