Ewald D Rose, Haldeman PhD Lauren A
The University of North Carolina at Greensboro, NC, USA.
Glob Pediatr Health. 2016 Feb 16;3:2333794X15625159. doi: 10.1177/2333794X15625159. eCollection 2016.
Hypertension is a complex and multifaceted disease, with many contributing factors. While diet and nutrition are important influences, the confounding effects of overweight and obesity, metabolic and genetic factors, racial and ethnic predispositions, socioeconomic status, cultural influences, growth rate, and pubertal stage have even more influence and make diagnosis quite challenging. The prevalence of hypertension in adolescents far exceeds the numbers who have been diagnosed; studies have found that 75% or more go undiagnosed. This literature review summarizes the challenges of blood pressure classification in adolescents, discusses the impact of these confounding influences, and identifies actions that will improve diagnosis and treatment outcomes.
高血压是一种复杂且多方面的疾病,有许多促成因素。虽然饮食和营养是重要影响因素,但超重和肥胖、代谢与遗传因素、种族和民族易感性、社会经济地位、文化影响、生长速率以及青春期阶段的混杂效应具有更大影响,使得诊断颇具挑战性。青少年高血压的患病率远远超过已被诊断出的人数;研究发现,75% 或更多的患者未被诊断出来。这篇文献综述总结了青少年血压分类的挑战,讨论了这些混杂影响的作用,并确定了可改善诊断和治疗结果的措施。