Rosén L, Ostergren J, Roald O K, Stranden E, Fagrell B
Department of Anesthesiology, University of Oslo, Aker Hospital, Norway.
Microvasc Res. 1989 May;37(3):289-97. doi: 10.1016/0026-2862(89)90047-2.
In a recent study we found skin capillary blood cell velocity (CBV) at rest, laser Doppler flux (LDF), and its response to lowering of the hand to be reduced in the dystrophic hand of patients suffering from sympathetic dystrophies. This study confirms these previous findings. Four of the 12 patients investigated felt intermittent pain in the "healthy" hand. Basal CBV, LDF, and reaction during dependency were not impaired in the asymptomatic hand compared with controls. However, during cooling of the contralateral hand CBV and LDF decreased significantly (median 44 and 37.5%) in the control group but neither in the affected nor in the asymptomatic hand among patients. Sympathetic blockade significantly increased both CBV and LDF in the dystrophic hand (median 58 and 20%), but no obvious beneficial symptomatic effect was noted. The lack of response to contralateral cooling in both hands indicates a disturbance of a central nervous mechanism in patients with unilateral sympathetic dystrophies.
在最近的一项研究中，我们发现，患有交感神经营养不良的患者，其患侧手部处于静止状态时的皮肤毛细血管血细胞速度（CBV）、激光多普勒血流灌注量（LDF）及其对手部下放的反应均有所降低。本研究证实了这些先前的发现。在接受调查的12名患者中，有4名在“健康”手部感到间歇性疼痛。与对照组相比，无症状手部的基础CBV、LDF以及下垂时的反应均未受损。然而，在对侧手部冷却期间，对照组的CBV和LDF显著下降（中位数分别为44%和37.5%），但患者的患侧手部和无症状手部均未出现这种情况。交感神经阻滞使营养不良手部的CBV和LDF均显著增加（中位数分别为58%和20%），但未观察到明显的有益症状改善效果。双手对侧冷却均无反应，这表明单侧交感神经营养不良患者存在中枢神经机制紊乱。
