Rothenberg S J, Schnaas L, Cansino-Ortiz S, Perroni-Hernández E, de la Torre P, Neri-Méndez C, Ortega P, Hidalgo-Loperena H, Svendsgaard D
Instituto Mexicano de Psiquiatría, Mexico City.
Neurotoxicol Teratol. 1989 Mar-Apr;11(2):85-93. doi: 10.1016/0892-0362(89)90046-9.
Gestation age and ability of the baby to self-quiet and to be consoled during the first 30 days of life decrease when mother's blood lead levels rise from 36 weeks of pregnancy to birth of child. These effects appear to be independent of the absolute lead levels of mother and child (N = 42). Since pre- and perinatal stress predicts higher maternal birth lead, further work could determine the relative contributions of undetected stress during pregnancy and elevated lead levels upon subsequent development. Several cases, not included in the statistical analyses, showed associations between cord leads greatly elevated over maternal leads and poor outcome.
从怀孕36周到孩子出生期间，母亲血铅水平升高时，婴儿的胎龄以及在出生后前30天内自我安静和被安抚的能力会降低。这些影响似乎与母亲和孩子的绝对铅水平无关（N = 42）。由于产前和围产期应激预示着母亲分娩时铅含量较高，进一步的研究可以确定孕期未检测到的应激和铅水平升高对后续发育的相对影响。统计分析中未纳入的几个案例显示，脐带血铅水平比母亲血铅水平大幅升高与不良后果之间存在关联。
