• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

2007 - 2010年韩国国家健康与营养检查调查（KNHANES）：绝经前后韩国女性血清铁蛋白水平与胰岛素抵抗的关系

The Relationship between Serum Ferritin Levels and Insulin Resistance in Pre- and Postmenopausal Korean Women: KNHANES 2007-2010.

作者信息

Kim Min Kyoung, Chon Seung Joo, Jung Yeon Soo, Kim Bo Ok, Noe Eun Bee, Yun Bo Hyon, Cho SiHyun, Choi Young Sik, Lee Byung Seok, Seo Seok Kyo

机构信息

Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

PLoS One. 2016 Jun 23;11(6):e0157934. doi: 10.1371/journal.pone.0157934. eCollection 2016.

DOI:10.1371/journal.pone.0157934
PMID:27337113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4919039/
Abstract

BACKGROUND

Serum ferritin levels increase in postmenopausal women, and they are reported to be linked to major health problems. Here, we investigated the association between serum ferritin levels and insulin resistance (IR) in postmenopausal women.

METHODS

A total of 6632 healthy Korean women (4357 premenopausal and 2275 postmenopausal) who participated in the Korean National Health and Nutrition Examination Survey (KNHANES) in 2007-2010 were enrolled in the study. Serum ferritin values were divided into six groups for the premenopausal and postmenopausal groups. IR and obesity indices were evaluated according to the six serum ferritin groups. Statistical analysis was carried out using SAS software, version 9.2 (SAS Institute Inc., Cary, NC, USA).

RESULTS

The association between the IR indices and ferritin groups had a higher level of statistical significance in the postmenopausal group than in the premenopausal group. In addition, for the postmenopausal group, the estimates increased significantly in the sixth ferritin group compared to those in the first ferritin group. However, the association between the obesity indices and ferritin levels was not significantly different between the premenopausal and postmenopausal groups.

CONCLUSION

Elevated serum ferritin levels were associated with an increased risk of insulin resistance in postmenopausal women.

摘要

背景

绝经后女性血清铁蛋白水平升高，据报道与主要健康问题有关。在此，我们研究了绝经后女性血清铁蛋白水平与胰岛素抵抗（IR）之间的关联。

方法

共有6632名健康韩国女性（4357名绝经前女性和2275名绝经后女性）参与了2007 - 2010年的韩国国家健康与营养检查调查（KNHANES）并被纳入本研究。血清铁蛋白值在绝经前和绝经后组中被分为六组。根据六个血清铁蛋白组评估胰岛素抵抗和肥胖指数。使用SAS软件9.2版（美国北卡罗来纳州卡里的SAS研究所）进行统计分析。

结果

胰岛素抵抗指数与铁蛋白组之间的关联在绝经后组中比在绝经前组中具有更高的统计学显著性水平。此外，对于绝经后组，与第一个铁蛋白组相比，第六个铁蛋白组的估计值显著增加。然而，绝经前和绝经后组之间肥胖指数与铁蛋白水平之间的关联没有显著差异。

结论

血清铁蛋白水平升高与绝经后女性胰岛素抵抗风险增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c5/4919039/1a98c04e5f92/pone.0157934.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c5/4919039/eff8b9c97439/pone.0157934.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c5/4919039/e5d66e7b39e6/pone.0157934.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c5/4919039/1a98c04e5f92/pone.0157934.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c5/4919039/eff8b9c97439/pone.0157934.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c5/4919039/e5d66e7b39e6/pone.0157934.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c5/4919039/1a98c04e5f92/pone.0157934.g003.jpg

相似文献

1
The Relationship between Serum Ferritin Levels and Insulin Resistance in Pre- and Postmenopausal Korean Women: KNHANES 2007-2010.2007 - 2010年韩国国家健康与营养检查调查（KNHANES）：绝经前后韩国女性血清铁蛋白水平与胰岛素抵抗的关系
PLoS One. 2016 Jun 23;11(6):e0157934. doi: 10.1371/journal.pone.0157934. eCollection 2016.
2
Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008.根据韩国 2008 年全国健康和营养调查，血清铁蛋白与韩国普通人群代谢综合征和糖尿病的关系。
Metabolism. 2011 Oct;60(10):1416-24. doi: 10.1016/j.metabol.2011.02.008. Epub 2011 Apr 12.
3
Serum ferritin level is positively associated with insulin resistance and metabolic syndrome in postmenopausal women: A nationwide population-based study.血清铁蛋白水平与绝经后女性的胰岛素抵抗和代谢综合征呈正相关：一项基于全国人口的研究。
Maturitas. 2017 Sep;103:3-7. doi: 10.1016/j.maturitas.2017.06.004. Epub 2017 Jun 12.
4
Gender difference in the relationship between the ferritin and homeostasis model assessment of insulin resistance in non-diabetic Korean adults.非糖尿病韩国成年人铁蛋白与稳态模型评估胰岛素抵抗关系中的性别差异。
PLoS One. 2018 Jun 27;13(6):e0199465. doi: 10.1371/journal.pone.0199465. eCollection 2018.
5
The association between the metabolic syndrome and iron status in pre- and postmenopausal women: Korean National Health and Nutrition Examination Survey (KNHANES) in 2012.代谢综合征与绝经前后妇女铁状态的关系：2012 年韩国国家健康和营养检查调查（KNHANES）。
Br J Nutr. 2022 Feb 28;127(4):630-640. doi: 10.1017/S0007114521001331. Epub 2021 Apr 26.
6
Gender difference in relationship between serum ferritin and 25-hydroxyvitamin D in Korean adults.韩国成年人血清铁蛋白与25-羟基维生素D之间关系的性别差异。
PLoS One. 2017 May 31;12(5):e0177722. doi: 10.1371/journal.pone.0177722. eCollection 2017.
7
Serum ferritin levels are associated with metabolic syndrome in postmenopausal women but not in premenopausal women.血清铁蛋白水平与绝经后妇女的代谢综合征相关，但与绝经前妇女无关。
Menopause. 2011 Oct;18(10):1120-4. doi: 10.1097/gme.0b013e318217e172.
8
Insulin Resistance Is Associated with Prevalence of Physician-Diagnosed Urinary Incontinence in Postmenopausal Non-Diabetic Adult Women: Data from the Fourth Korea National Health and Nutrition Examination Survey.胰岛素抵抗与绝经后非糖尿病成年女性医生诊断的尿失禁患病率相关：来自韩国第四次全国健康与营养检查调查的数据。
PLoS One. 2015 Nov 3;10(11):e0141720. doi: 10.1371/journal.pone.0141720. eCollection 2015.
9
High serum ferritin levels are associated with metabolic risk factors in non-obese Korean young adults: Korean National Health and Nutrition Examination Survey (KNHANES) IV.血清铁蛋白水平与非肥胖韩国年轻成年人代谢危险因素的相关性：韩国国家健康和营养检查调查（KNHANES）IV。
Clin Endocrinol (Oxf). 2012 Aug;77(2):233-40. doi: 10.1111/j.1365-2265.2011.04248.x.
10
Association between serum osteocalcin and insulin resistance in postmenopausal, but not premenopausal, women in Korea.韩国绝经后女性的血清骨钙素与胰岛素抵抗的关系，但在绝经前女性中并非如此。
Menopause. 2013 Oct;20(10):1061-6. doi: 10.1097/GME.0b013e31828838e8.

引用本文的文献

1
Correction: The Relationship between Serum Ferritin Levels and Insulin Resistance in Pre- and Postmenopausal Korean Women: KNHANES 2007-2010.更正：韩国绝经前后女性血清铁蛋白水平与胰岛素抵抗的关系：韩国国家健康与营养检查调查（KNHANES）2007 - 2010年
PLoS One. 2016 Jul 26;11(7):e0160300. doi: 10.1371/journal.pone.0160300. eCollection 2016.

本文引用的文献

1
Iron status in obesity: An independent association with metabolic parameters and effect of weight loss.肥胖中的铁状态：与代谢参数的独立关联及体重减轻的影响。
Nutr Metab Cardiovasc Dis. 2015 Jun;25(6):541-7. doi: 10.1016/j.numecd.2015.02.012. Epub 2015 Mar 4.
2
Association between levels of serum ferritin and bone mineral density in Korean premenopausal and postmenopausal women: KNHANES 2008-2010.韩国绝经前和绝经后女性血清铁蛋白水平与骨矿物质密度之间的关联：韩国国家健康与营养检查调查2008 - 2010年
PLoS One. 2014 Dec 18;9(12):e114972. doi: 10.1371/journal.pone.0114972. eCollection 2014.
3
Clinical significance of serum ferritin level as an independent predictor of insulin resistance in Korean men.
血清铁蛋白水平作为韩国男性胰岛素抵抗的独立预测因子的临床意义。
Diabetes Res Clin Pract. 2015 Jan;107(1):187-93. doi: 10.1016/j.diabres.2014.08.022. Epub 2014 Sep 6.
4
Iron metabolism is prospectively associated with insulin resistance and glucose intolerance over a 7-year follow-up period: the CODAM study.在一项为期7年的随访研究（CODAM研究）中，铁代谢与胰岛素抵抗及葡萄糖耐量异常存在前瞻性关联。
Acta Diabetol. 2015 Apr;52(2):337-48. doi: 10.1007/s00592-014-0646-3. Epub 2014 Oct 1.
5
Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women.韩国绝经后女性血清铁蛋白水平与代谢综合征及亚临床冠状动脉粥样硬化的关联
Clin Chim Acta. 2015 Jan 1;438:62-6. doi: 10.1016/j.cca.2014.07.042. Epub 2014 Aug 6.
6
The role of oxidative stress in menopause.氧化应激在更年期的作用。
J Midlife Health. 2013 Jul;4(3):140-6. doi: 10.4103/0976-7800.118990.
7
Iron overload causes oxidative stress and impaired insulin signaling in AML-12 hepatocytes.铁过载导致 AML-12 肝细胞氧化应激和胰岛素信号受损。
Dig Dis Sci. 2013 Jul;58(7):1899-908. doi: 10.1007/s10620-013-2648-3. Epub 2013 Apr 5.
8
Serum ferritin is associated with markers of insulin resistance in Japanese men but not in women.血清铁蛋白与日本男性的胰岛素抵抗标志物相关，但与女性无关。
Metabolism. 2013 Apr;62(4):561-7. doi: 10.1016/j.metabol.2012.07.025. Epub 2012 Oct 27.
9
Serum ferritin level is associated with the prevalence of metabolic syndrome in Korean adults: the 2007-2008 Korean National Health and Nutrition Examination Survey.血清铁蛋白水平与韩国成年人代谢综合征的患病率相关：2007-2008 年韩国国家健康和营养检查调查。
Clin Chim Acta. 2012 Mar 22;413(5-6):636-41. doi: 10.1016/j.cca.2011.12.011. Epub 2011 Dec 23.
10
Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008.根据韩国 2008 年全国健康和营养调查，血清铁蛋白与韩国普通人群代谢综合征和糖尿病的关系。
Metabolism. 2011 Oct;60(10):1416-24. doi: 10.1016/j.metabol.2011.02.008. Epub 2011 Apr 12.