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催化不对称反应与醌类化合物的合成。

Catalytic asymmetric reactions and synthesis of quinones.

作者信息

Hosamani Basavaprabhu, Ribeiro Matheus F, da Silva Júnior Eufrânio N, Namboothiri Irishi N N

机构信息

Department of Chemistry, Indian Institute of Technology Bombay, Mumbai-400076, India.

出版信息

Org Biomol Chem. 2016 Aug 7;14(29):6913-31. doi: 10.1039/c6ob01119e. Epub 2016 Jun 23.

Abstract

Asymmetric reactions and the synthesis of various quinones, carried out in the presence of chiral organocatalysts and metal-ligand complexes, are reviewed here. The role of quinones as Michael donors/acceptors, Diels-Alder dienophiles and 1,3-dipolarophiles has been extensively investigated to access complex structural frameworks. Additionally, reports in the literature on the stereoselective synthesis of simple and complex quinoidal compounds with potential biological activities have also been summarized in this review.

摘要

本文综述了在手性有机催化剂和金属-配体配合物存在下进行的不对称反应以及各种醌类的合成。醌作为迈克尔供体/受体、狄尔斯-阿尔德亲双烯体和1,3-偶极环加成亲偶极体的作用已得到广泛研究,以构建复杂的结构框架。此外,本综述还总结了文献中关于具有潜在生物活性的简单和复杂醌类化合物的立体选择性合成的报道。

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