St John Alexander E, Rowhani-Rahbar Ali, Arbabi Saman, Bulger Eileen M
Division of Emergency Medicine, Department of Medicine, University of Washington, Seattle, Washington.
Department of Epidemiology, University of Washington, Seattle, Washington; Harborview Injury Prevention Center, Seattle, Washington.
J Surg Res. 2016 Jun 1;203(1):95-102. doi: 10.1016/j.jss.2016.01.036. Epub 2016 Feb 4.
Elderly trauma patients suffer worse outcomes than younger patients. Trauma team activation (TTA) improves outcomes in younger patients. It is unclear whether decreased TTA effectiveness or under-activation in elderly patients could contribute to their poor outcomes.
This retrospective registry study examined all adult trauma patients admitted to a level 1 trauma center over 2 y. Analyses tested (1) whether age modifies the effect of TTA on poor outcomes, (2) whether elderly patients with severe injury were less likely to receive TTA than younger patients, and (3) which early variables were associated with poor outcomes among elderly patients who did not receive TTA.
The study included 10,033 patients. The adjusted relative risk from TTA for all ages was 0.48 (95% confidence interval (CI) = 0.34-0.68, P < 0.001), and there was no effect modification by age (interaction term P value, 0.171). The adjusted odds ratio for the young was 0.49 (95% CI = 0.26-0.91, P = 0.024) and for the elderly was 0.80 (95% CI = 0.53-1.20, P = 0.282). The adjusted odds ratio for lack of TTA associated with old age was 1.37 (95% CI = 1.12-1.69, P = 0.003). The strongest associations with poor outcomes were seen with low heart rate, low minimum blood pressure, high injury severity score, and high Glasgow coma score.
Lack of TTA could contribute to elderly patients' poor outcomes. Clinicians should not be reassured by normal heart rates and should be wary of even transiently lower blood pressures in the elderly. A large cohort study is needed to identify which additional elderly patients could benefit from TTA.
老年创伤患者的预后比年轻患者更差。创伤团队启动(TTA)可改善年轻患者的预后。目前尚不清楚老年患者中TTA有效性降低或启动不足是否会导致其预后不良。
这项回顾性登记研究对2年期间入住一级创伤中心的所有成年创伤患者进行了检查。分析测试了(1)年龄是否会改变TTA对不良预后的影响,(2)重伤老年患者接受TTA的可能性是否低于年轻患者,以及(3)在未接受TTA的老年患者中,哪些早期变量与不良预后相关。
该研究纳入了10,033名患者。所有年龄段TTA调整后的相对风险为0.48(95%置信区间(CI)=0.34-0.68,P<0.001),且不存在年龄对效应的修饰作用(交互项P值为0.171)。年轻人调整后的优势比为0.49(95%CI=0.26-0.91,P=0.024),老年人为0.80(95%CI=0.53-1.20,P=0.282)。与老年相关的未进行TTA的调整后优势比为1.37(95%CI=1.12-1.69,P=0.003)。与不良预后关联最强的因素是心率低、最低血压低、损伤严重程度评分高和格拉斯哥昏迷评分高。
未进行TTA可能导致老年患者预后不良。临床医生不应因心率正常而放心,对于老年人即使是短暂的血压降低也应保持警惕。需要进行一项大型队列研究,以确定哪些其他老年患者可从TTA中获益。