Glasner-Edwards Suzette, Patrick Kevin, Ybarra Michele L, Reback Cathy J, Rawson Richard A, Chokron Garneau Helene, Chavez Kathryn, Venegas Alexandra
Integrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, United States.
JMIR Res Protoc. 2016 Jun 24;5(2):e131. doi: 10.2196/resprot.5407.
Evidence-based psychosocial interventions for addictions and related conditions such as cognitive behavioral therapy (CBT) are underutilized. Obstacles to implementation of CBT in clinical settings include limited availability of quality training, supervision, and certification in CBT for clinicians; high rates of clinician turnover and high caseloads; and limited qualifications of the workforce to facilitate CBT expertise.
Mobile phone-based delivery of CBT, if demonstrated to be feasible and effective, could be transformative in broadening its application and improving the quality of addiction treatment. No experimental interventions that deliver CBT targeting both drug use and medication adherence using text messaging have been previously reported; as such, the objective of this study is to develop and test an SMS-based treatment program for HIV-positive adults with comorbid substance use disorders.
With user input, we developed a 12-week CBT-based text messaging intervention (TXT-CBT) targeting antiretroviral (ART) adherence, risk behaviors, and drug use in a population of HIV-infected substance users.
The intervention has been developed and is presently being tested in a pilot randomized clinical trial. Results will be reported later this year.
This investigation will yield valuable knowledge about the utility of a cost-effective, readily deployable text messaging behavioral intervention for HIV-infected drug users.
基于证据的针对成瘾及相关病症的心理社会干预措施，如认知行为疗法（CBT），未得到充分利用。在临床环境中实施CBT的障碍包括临床医生获得CBT高质量培训、督导和认证的机会有限；临床医生更替率高且工作量大；以及工作人员促进CBT专业知识的资质有限。
如果基于手机的CBT交付被证明是可行且有效的，那么在扩大其应用范围和提高成瘾治疗质量方面可能具有变革性。此前尚无使用短信传递针对药物使用和药物依从性的CBT的实验性干预措施的报道；因此，本研究的目的是为合并物质使用障碍的HIV阳性成年人开发并测试一种基于短信的治疗方案。
在用户的参与下，我们针对HIV感染的物质使用者群体，开发了一种为期12周、基于CBT的短信干预措施（TXT-CBT），旨在提高抗逆转录病毒治疗（ART）的依从性、降低风险行为以及减少药物使用。
该干预措施已开发完成，目前正在一项试点随机临床试验中进行测试。结果将于今年晚些时候公布。
本调查将为针对HIV感染吸毒者的具有成本效益且易于部署的短信行为干预措施的效用提供有价值的知识。
