Division of Epidemiology and Community Health, University of Minnesota, 1300 S. 2nd Street, Suite 300, Minneapolis, MN, USA.
Division of Infectious Diseases, Hennepin Healthcare, Minneapolis, MN, USA.
AIDS Behav. 2019 Nov;23(11):3184-3198. doi: 10.1007/s10461-019-02597-3.
APP+ is a theoretically-grounded mobile app intervention to improve antiretroviral (ART) adherence among men who have sex with men (MSM) who use stimulants. We assessed the feasibility and acceptability of APP+ in a six-month randomized controlled trial among a national sample of 90 MSM recruited online; secondarily, we examined changes in self-reported ART adherence by study arm. Retention at the final assessment was 82%, and acceptability ratings were comparable to other technology-based interventions. MSM in the APP+ group reported higher self-reported percentage ART adherence in the past 30 days at the four-month timepoint compared to a no-treatment control group (89.0% vs. 77.2%). However, once access to the app was removed after month four, group differences in ART adherence diminished by month six. APP+ may be a potentially promising intervention approach for MSM living with HIV who use stimulants but would require enhancements to optimize acceptability and demonstrate more sustained effects.
APP+ 是一种基于理论的手机应用程序干预措施，旨在提高使用兴奋剂的男男性行为者（MSM）的抗逆转录病毒（ART）治疗依从性。我们在一项针对 90 名在线招募的 MSM 的为期六个月的随机对照试验中评估了 APP+ 的可行性和可接受性；其次，我们检查了研究组中自我报告的 ART 治疗依从性的变化。最后评估时的保留率为 82%，可接受性评分与其他基于技术的干预措施相当。与无治疗对照组相比，APP+ 组的 MSM 在第四个月时报告过去 30 天内自我报告的 ART 治疗依从性更高（89.0% vs. 77.2%）。然而，在第四个月后停用该应用程序后，到第六个月时，ART 治疗依从性的组间差异就缩小了。APP+ 可能是一种有前途的针对使用兴奋剂的 HIV 感染者的干预方法，但需要改进以提高可接受性并展示更持久的效果。
