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溶血嗜麦芽窄食单胞菌/水生嗜麦芽窄食单胞菌引起的小儿菌血症。

Pediatric bacteremia caused by Chromobacterium haemolyticum/Chromobacterium aquaticum.

作者信息

Harmon Nicole, Mortensen Joel E, Robinette Eric, Powell Eleanor A

机构信息

Diagnostic Infectious Disease Testing Laboratory, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Diagnostic Infectious Disease Testing Laboratory, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

出版信息

Diagn Microbiol Infect Dis. 2016 Sep;86(1):108-11. doi: 10.1016/j.diagmicrobio.2016.05.021. Epub 2016 Jun 3.

Abstract

We present a case of pediatric bacteremia caused by Chromobacterium haemolyticum, a β-hemolytic, non-pigmented, Gram-negative bacilli recovered from a blood culture and initially identified as Chromobacterium violaceum using phenotypic and proteomic methods. 16S rRNA sequencing of the patient isolated demonstrated a high degree of sequence homology with the type strain of C. haemolyticum. The patient recovered following treatment with meropenem, gentamicin, and trimethoprim/sulfamethoxazole. This case highlights the potential misidentification of C. haemolyticum as non-pigmented C. violaceum due to limitations of the currently available identification methodologies.

摘要

我们报告了一例由溶血色素杆菌引起的小儿菌血症病例。溶血色素杆菌是一种β溶血性、无色素、革兰氏阴性杆菌,从血培养中分离出来,最初使用表型和蛋白质组学方法鉴定为紫色色杆菌。对患者分离株进行的16S rRNA测序显示,其与溶血色素杆菌模式菌株具有高度的序列同源性。患者在接受美罗培南、庆大霉素和甲氧苄啶/磺胺甲恶唑治疗后康复。该病例凸显了由于现有鉴定方法的局限性,溶血色素杆菌可能被误鉴定为无色素的紫色色杆菌。

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