Harmon Nicole, Mortensen Joel E, Robinette Eric, Powell Eleanor A
Diagnostic Infectious Disease Testing Laboratory, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Diagnostic Infectious Disease Testing Laboratory, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Diagn Microbiol Infect Dis. 2016 Sep;86(1):108-11. doi: 10.1016/j.diagmicrobio.2016.05.021. Epub 2016 Jun 3.
We present a case of pediatric bacteremia caused by Chromobacterium haemolyticum, a β-hemolytic, non-pigmented, Gram-negative bacilli recovered from a blood culture and initially identified as Chromobacterium violaceum using phenotypic and proteomic methods. 16S rRNA sequencing of the patient isolated demonstrated a high degree of sequence homology with the type strain of C. haemolyticum. The patient recovered following treatment with meropenem, gentamicin, and trimethoprim/sulfamethoxazole. This case highlights the potential misidentification of C. haemolyticum as non-pigmented C. violaceum due to limitations of the currently available identification methodologies.
我们报告了一例由溶血色素杆菌引起的小儿菌血症病例。溶血色素杆菌是一种β溶血性、无色素、革兰氏阴性杆菌,从血培养中分离出来,最初使用表型和蛋白质组学方法鉴定为紫色色杆菌。对患者分离株进行的16S rRNA测序显示,其与溶血色素杆菌模式菌株具有高度的序列同源性。患者在接受美罗培南、庆大霉素和甲氧苄啶/磺胺甲恶唑治疗后康复。该病例凸显了由于现有鉴定方法的局限性,溶血色素杆菌可能被误鉴定为无色素的紫色色杆菌。