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黄石国家公园附近温泉引起的出血败血性巴斯德菌感染:病例报告。

Chromobacterium haemolyticum infection from hot springs near Yellowstone National Park: a case report.

机构信息

Eastern Idaho Regional Medical Center, 3100 Channing Way, Idaho Falls, ID, 83404, USA.

HCA Healthcare, 4900 S. Monaco St., Denver, CO, 80237, USA.

出版信息

J Med Case Rep. 2023 Jun 23;17(1):259. doi: 10.1186/s13256-023-04005-w.

DOI:10.1186/s13256-023-04005-w
PMID:37349786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10288766/
Abstract

BACKGROUND

Chromobacterium haemolyticum is a gram-negative anaerobic sporulated rod and was only first identified in 2008. It is very rare in people with only a handful of cases having been diagnosed around the world.

CASE PRESENTATION

After suffering a fall near Yellowstone National Park, a white male patient in his 50 s presented to a hospital in Eastern Idaho. With many unexplained symptoms, several changes in patient stability and recovery, over a course of 18 days in the hospital, the infecting organism could not be easily identified. Labs in the hospital, state, and eventually outside of the state were consulted for pathogen identification, which was only accomplished after the patient was discharged.

CONCLUSIONS

To our knowledge, this is only the seven reported human infection with Chromobacterium haemolyticum. This bacterium is difficult to identify and may be occur in rural areas without the proper testing facilities to quickly identify the pathogen, which is essential to timely treatment.

摘要

背景

噬血性克氏杆菌是革兰氏阴性厌氧芽胞杆菌,于 2008 年首次被发现。噬血性克氏杆菌在人群中非常罕见,全世界仅有少数几例确诊。

病例介绍

一名 50 多岁的白人男性在黄石国家公园附近摔倒后,到爱达荷州东部的一家医院就诊。在医院接受治疗的 18 天里,患者出现了许多不明原因的症状,病情和恢复情况多次发生变化,由于无法轻易确定感染源,医院、州内和州外的实验室都对病原体进行了检测,但直到患者出院后才得以确诊。

结论

据我们所知,这是仅有的七例噬血性克氏杆菌所致人类感染报告。这种细菌难以识别,可能发生在农村地区,这些地区没有适当的检测设施来快速识别病原体,而这对及时治疗至关重要。

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本文引用的文献

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J Med Case Rep. 2023 Apr 30;17(1):171. doi: 10.1186/s13256-023-03913-1.
2
Chromobacterium haemolyticum Pneumonia Associated with Near-Drowning and River Water, Japan.溶血杆菌肺炎与近乎溺水和河水有关,日本。
Emerg Infect Dis. 2020 Sep;26(9):2186-2189. doi: 10.3201/eid2609.190670.
3
Production of N-acyl homoserine lactones by Chromobacterium haemolyticum KM2 isolated from the river water in Malaysia.从马来西亚河水中分离出的溶血色杆菌KM2产生N-酰基高丝氨酸内酯。
Arch Microbiol. 2018 Sep;200(7):1135-1142. doi: 10.1007/s00203-018-1526-y. Epub 2018 May 23.
4
Pediatric bacteremia caused by Chromobacterium haemolyticum/Chromobacterium aquaticum.溶血嗜麦芽窄食单胞菌/水生嗜麦芽窄食单胞菌引起的小儿菌血症。
Diagn Microbiol Infect Dis. 2016 Sep;86(1):108-11. doi: 10.1016/j.diagmicrobio.2016.05.021. Epub 2016 Jun 3.
5
Chromobacterium haemolyticum Pneumonia Possibly Due to the Aspiration of Runoff Water.溶血色杆菌肺炎可能因吸入径流污水所致。
Jpn J Infect Dis. 2015;68(6):526-9. doi: 10.7883/yoken.JJID.2014.285. Epub 2015 Jun 12.
6
First pediatric case of Chromobacterium haemolyticum causing proctocolitis.首例由溶血色素杆菌引起小儿直肠结肠炎的病例。
Pediatr Int. 2014 Aug;56(4):615-7. doi: 10.1111/ped.12301.
7
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