Yu Cheng-Cheng, Liu Peng, Huang Da-Geng, Jiang Yong-Hong, Feng Hang, Hao Ding-Jun
Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China.
Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China.
Spine J. 2016 Nov;16(11):1384-1391. doi: 10.1016/j.spinee.2016.06.019. Epub 2016 Jun 23.
The study aimed to build a new cervical artificial disc C3-C7 segment prosthesis, and perform a biomechanical comparison between the new prosthesis and the Prestige LP prosthesis using a three-dimensional non-linear finite element (FE) model.
The study compared the biomechanical differences between the new cervical artificial disc prosthesis based on the physiological curvature of the end plate and the Prestige LP prosthesis after artificial disc replacement.
There has been no prior research on artificial disc prostheses based on the physiological curvature of the end plate; studies of biomechanical changes after cervical disc arthroplasty (CDR) are few.
An FE model of the C3-C7 segments was developed and validated. A new cervical artificial disc prosthesis based on the physiological curvature of the end plate and the Prestige LP prosthesis were integrated at the C5-C6 segment into the validated FE model. All models were subjected to a follower load of 73.6 N and a 1 Nm in flexion-extension, lateral bending, and axial torsion. The segmental range of motion (ROM) and stress on the prostheses were analyzed.
The ROM in most segments after CDR with new cervical artificial disc prosthesis was more similar to that of the normal cervical spine than the Prestige LP prosthesis. However, there was no significant difference between the two prostheses. The stress on the new artificial disc was significantly less than that in the Prestige LP prosthesis.
There was no significant difference in ROM in all segments after CDR for the two prostheses. The stress on the new cervical artificial disc prosthesis based on the physiological curvature of the end plate was significantly less than that in the Prestige LP prosthesis. The new artificial disc prosthesis is feasible and effective, and can reduce the implant-bone interface stress on the end plate, which may be one of the causes of prosthesis subsidence.
本研究旨在构建一种新型颈椎人工椎间盘C3 - C7节段假体，并使用三维非线性有限元（FE）模型对新型假体与Prestige LP假体进行生物力学比较。
本研究比较了基于终板生理曲度的新型颈椎人工椎间盘假体与人工椎间盘置换术后Prestige LP假体之间的生物力学差异。
此前尚无基于终板生理曲度的人工椎间盘假体的相关研究；颈椎间盘置换术（CDR）后生物力学变化的研究较少。
建立并验证了C3 - C7节段的FE模型。将基于终板生理曲度的新型颈椎人工椎间盘假体和Prestige LP假体在C5 - C6节段整合到经过验证的FE模型中。所有模型在屈伸、侧弯和轴向扭转时均承受73.6 N的随动载荷和1 Nm的扭矩。分析假体的节段活动范围（ROM）和应力。
使用新型颈椎人工椎间盘假体进行CDR后，大多数节段的ROM比Prestige LP假体更接近正常颈椎。然而，两种假体之间无显著差异。新型人工椎间盘上的应力明显小于Prestige LP假体。
两种假体CDR后所有节段的ROM无显著差异。基于终板生理曲度的新型颈椎人工椎间盘假体上的应力明显小于Prestige LP假体。新型人工椎间盘假体可行且有效，可降低终板上种植体 - 骨界面应力，这可能是假体下沉的原因之一。
