Passaretti S, Mazzotti G, de Franchis R, Cipolla M, Testoni P A, Tittobello A
Gastroenterology Unit, University of Milan, Italy.
Scand J Gastroenterol. 1989 Apr;24(3):334-8. doi: 10.3109/00365528909093056.
Esophageal manometry was performed in 45 cirrhotics with varices, in 15 cirrhotics without varices, and in 20 normal subjects, to define the effect of varices on esophageal motility. Cirrhotics with varices showed a decreased amplitude of motor waves in the lower half of the esophagus (p less than 0.01), an increased duration of primary peristaltic waves along the entire length of the esophagus (upper esophagus, p less than 0.05; lower esophagus, p less than 0.01), and an increased peak-to-peak speed of primary peristaltic waves (p less than 0.01). Resting lower esophageal sphincter pressure and duration of sphincter relaxation were similar in patients and controls. The above-mentioned abnormalities might be due to the mechanical effect of the presence of varices.
对45例伴有静脉曲张的肝硬化患者、15例不伴有静脉曲张的肝硬化患者以及20名正常受试者进行食管测压，以确定静脉曲张对食管动力的影响。伴有静脉曲张的肝硬化患者食管下半段运动波振幅降低（p<0.01），食管全长原发性蠕动波持续时间增加（食管上段，p<0.05；食管下段，p<0.01），原发性蠕动波峰峰值速度增加（p<0.01）。患者和对照组的静息下食管括约肌压力及括约肌松弛持续时间相似。上述异常可能是由于静脉曲张存在的机械效应所致。
