Ogle S J, Kirk C J, Bailey R J, Johnson A G, Williams R, Murray-Lyon I M
Digestion. 1978;18(3-4):178-85. doi: 10.1159/000198200.
Oesophageal function has been studied in three groups of cirrhotic patients: those without varices, those with varices and those with varices treated by injection sclerotherapy. Using the Honeywell Model 31 oesophageal motility probe and the Ingold combined stomach pH electrode, measurements were made of the lower oesophageal sphincter (LES) pressure and length, swallowing responses, reflux and clearance of acid. The presence of varices was associated with an increase in LES length and reduced lower oesophageal contraction pressure during swallowing and some failure of sphincter relaxation during swallowing. Sclerotherapy was associated with a reduction in the maximum LES pressure both at rest and during swallowing, and an impairment of acid clearance, but postural reflux of acid was not observed in any patient.
无静脉曲张的患者、有静脉曲张的患者以及接受注射硬化疗法治疗静脉曲张的患者。使用霍尼韦尔31型食管动力探头和英戈尔德联合胃pH电极，测量了食管下括约肌（LES）压力和长度、吞咽反应、反流以及酸清除情况。静脉曲张的存在与LES长度增加、吞咽时食管下段收缩压力降低以及吞咽时括约肌松弛部分功能障碍有关。硬化疗法与静息和吞咽时LES最大压力降低以及酸清除受损有关，但未在任何患者中观察到酸的体位性反流。
