Ponzetto Federico, Giraud Sylvain, Leuenberger Nicolas, Boccard Julien, Nicoli Raul, Baume Norbert, Rudaz Serge, Saugy Martial
Front Horm Res. 2016;47:153-67. doi: 10.1159/000445177. Epub 2016 Jun 27.
Over the past few years, the World Anti-Doping Agency (WADA) has focused its efforts on detecting not only small prohibited molecules, but also larger endogenous molecules such as hormones, in the view of implementing an endocrinological module in the Athlete Biological Passport (ABP). In this chapter, the detection of two major types of hormones used for doping, growth hormone (GH) and endogenous anabolic androgenic steroids (EAASs), will be discussed: a brief historical background followed by a description of state-of-the-art methods applied by accredited anti-doping laboratories will be provided and then current research trends outlined. In addition, microRNAs (miRNAs) will also be presented as a new class of biomarkers for doping detection.
