Lamers Susanna L, Barbier Andrew E, Ratmann Oliver, Fraser Christophe, Rose Rebecca, Laeyendecker Oliver, Grabowski Mary K
1 Bioinfoexperts, LLC , Thibodaux, Louisiana.
2 Medical Research Council Centre for Outbreak Analysis and Modeling, Department of Infectious Disease Epidemiology, Imperial College London , London, United Kingdom .
AIDS Res Hum Retroviruses. 2016 Sep;32(9):904-8. doi: 10.1089/AID.2016.0079. Epub 2016 Aug 2.
Central and Eastern African HIV sequence data have been most critical in understanding the establishment and evolution of the global HIV pandemic. Here we report on the extent of publicly available HIV genetic sequence data in the Los Alamos National Laboratory Sequence Database sampled from 1959 to 2013 from six African countries: Uganda, Kenya, Tanzania, Burundi, the Democratic Republic of Congo, and Rwanda. We have summarized these data, including HIV subtypes, the years sampled, and the genomic regions sequenced. We also provide curated alignments for this important geographic area in five HIV genomic regions with substantial coverage.
中非和东非的艾滋病毒序列数据对于理解全球艾滋病毒大流行的形成和演变最为关键。在此,我们报告了洛斯阿拉莫斯国家实验室序列数据库中1959年至2013年期间从六个非洲国家(乌干达、肯尼亚、坦桑尼亚、布隆迪、刚果民主共和国和卢旺达)采集的公开可用艾滋病毒基因序列数据的范围。我们总结了这些数据,包括艾滋病毒亚型、采样年份和测序的基因组区域。我们还为这个重要地理区域的五个艾滋病毒基因组区域提供了有大量覆盖的精心整理的比对。