Talib Ahmed Karim, Yui Yoshiaki, Kaneshiro Takashi, Sekiguchi Yukio, Nogami Akihiko, Aonuma Kazutaka
Division of Cardiovascular Medicine, Faculty of Medicine, Tsukuba University, 1-1-1, Tennodai Tsukuba, Japan.
J Arrhythm. 2016 Jun;32(3):220-2. doi: 10.1016/j.joa.2015.12.008. Epub 2016 Feb 8.
Placement of an implantable cardioverter-defibrillator (ICD) is the only powerful treatment modality for Brugada syndrome in patients presenting with ventricular fibrillation (VF). For those whose first presentation is an electrical storm, pharmacologic therapy is typically used to control VF followed by ICD implantation. We report an alternative approach whereby, before ICD implantation, emergency catheter ablation of the VF-triggering premature ventricular contraction (PVC) resulted in long-term VF-free survival. The results suggest that, because VF triggers appear in a narrow time window, ablation of the culprit PVCs that initiate VF before the index PVCs subside is a reasonable alternative approach.
对于出现心室颤动(VF)的 Brugada 综合征患者,植入式心脏复律除颤器(ICD)是唯一有效的治疗方式。对于首次发作即出现电风暴的患者,通常先采用药物治疗控制室颤,随后植入 ICD。我们报告了一种替代方法,即在植入 ICD 之前,对引发室颤的室性早搏(PVC)进行紧急导管消融,从而实现长期无室颤生存。结果表明,由于室颤触发因素出现在狭窄的时间窗内,在索引 PVC 消退之前对引发室颤的罪犯 PVC 进行消融是一种合理的替代方法。