Luo Yue-hua, Ma Shuang-cheng, Hu Shou-rong, Fu Hui-zheng, Zhou Zhi-qiang, Chen Wei-kang
Zhong Yao Cai. 2015 Nov;38(11):2306-10.
To study the chemical constituents of Callicarpa nudiflora.
The chemical constituents were isolated and purified by column chromatography on silica gel, ODS, Sephadex LH-20 and MPLC. Their structures were elucidated on the basis of physicochemical properties and special analysis.
Eleven compounds were isolated from the leaves of Callicarpa nudiflora, whose structures were elucidated as 2α,3α-dihydroxyurs-12-en-28-oic acid (1), isorhamnetin (2), 2α,3β,19α-trihydroxyurs-12-en-28-oic acid(3), 2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid(4), 2α,3α,19α-trihyhydroxy-olean-12-en-28-O-α-D-glucopyranoside (5), benzyl-4'-hydroxy-benzoyl-3'-O-β-D-glucopyranoside(6) (3S,5R,6R,7E,9S)-megastigman-7-ene-3,5,6,9-tetrol(7), philonotisflavone(8), 1, 6-di-O-caffeoyl-β-D-glucopyranoside (9), luteolin-4'-O-(6"-E-caffeoyl)-β-D-glucopyranoside (10), and (6S, 9R)-roseoside(11).
All compounds are isolated from this plant for the first time.
研究裸花紫珠的化学成分。
采用硅胶柱色谱、ODS柱色谱、葡聚糖凝胶LH - 20柱色谱及中压液相色谱等方法对化学成分进行分离纯化，并根据理化性质和波谱分析确定其结构。
从裸花紫珠叶中分离得到11个化合物，分别鉴定为2α,3α - 二羟基乌苏 - 12 - 烯 - 28 - 酸（1）、异鼠李素（2）、2α,3β,19α - 三羟基乌苏 - 12 - 烯 - 28 - 酸（3）、2α,3α,19α,23 - 四羟基乌苏 - 12 - 烯 - 28 - 酸（4）、2α,3α,19α - 三羟基齐墩果 - 12 - 烯 - 28 - O - α - D - 吡喃葡萄糖苷（5）、苄基 - 4'- 羟基 - 苯甲酰基 - 3'- O - β - D - 吡喃葡萄糖苷（6）、(3S,5R,6R,7E,9S) - 大牻牛儿烯 - 7 - 烯 - 3,5,6,9 - 四醇（7）、泽兰黄酮（8）、1,6 - 二 - O - 咖啡酰基 - β - D - 吡喃葡萄糖苷（9）、木犀草素 - 4'- O - (6'' - E - 咖啡酰基) - β - D - 吡喃葡萄糖苷（10）和(6S,9R) - 玫瑰糖苷（11）。
所有化合物均为首次从该植物中分离得到。
