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发育中小脑定量成像的新见解。

Novel insights from quantitative imaging of the developing cerebellum.

作者信息

Allin Matthew P G

机构信息

Camden and Islington NHS Foundation Trust, London, UK; King's College London, London, UK.

出版信息

Semin Fetal Neonatal Med. 2016 Oct;21(5):333-8. doi: 10.1016/j.siny.2016.06.003. Epub 2016 Jun 26.

DOI:10.1016/j.siny.2016.06.003
PMID:27357079
Abstract

There is increasing evidence that points to the central role of the cerebellum in many areas of human behaviour - in health and in illness. The findings reviewed here shed further light on the developmental vulnerability of cerebellar cell types, and highlight the new imaging techniques being used in this research. This article reviews some new advances in our understanding of the normal cerebellar growth trajectory, and how this may become disturbed by pathological processes. Cerebellar development is now being implicated in many conditions, from autism and other neuropsychiatric disorders to diabetes.

摘要

越来越多的证据表明,小脑在人类行为的许多领域(包括健康和疾病方面)都起着核心作用。本文回顾的研究结果进一步揭示了小脑细胞类型在发育过程中的脆弱性,并突出了该研究中使用的新成像技术。本文回顾了我们对正常小脑生长轨迹的一些新认识,以及这种轨迹如何可能因病理过程而受到干扰。现在,小脑发育与许多疾病有关,从自闭症和其他神经精神疾病到糖尿病。

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