Callegari Camilla, Ielmini M, Bianchi L, Lucano M, Bertù Lorenza, Vender Simone
Funct Neurol. 2016 Apr-Jun;31(2):87-93. doi: 10.11138/fneur/2016.31.2.087.
The authors set out to examine qualitatively the use of antiepileptic drugs (AEDs) in a population of older adults in a nursing home setting, evaluating aspects such as specialist prescriptions and changes in dosage. This retrospective prevalence study was carried out in a state-funded nursing home that provides care and rehabilitation for elderly people. The first objective of the study was to determine the prevalence of AED use in this population. The second objective was to monitor AED dosage modifications during the fifteen-month study period, focusing on the safety and the tolerability of AEDs. In the period of time considered, 129 of 402 monitored patients received at least one anti-epileptic therapy. The prevalence of AED use was therefore 32%. Gabapentin was found to be the most commonly prescribed drug, with a frequency of 29%, and it was used mainly for anxiety disorders, psychosis, neuropathic pain and mood disorders.
作者着手对疗养院环境中老年人群抗癫痫药物（AEDs）的使用情况进行定性研究，评估专科处方和剂量变化等方面。这项回顾性患病率研究在一家为老年人提供护理和康复服务的国有疗养院开展。该研究的首要目标是确定该人群中AEDs的使用患病率。第二个目标是在为期15个月的研究期间监测AEDs的剂量调整情况，重点关注AEDs的安全性和耐受性。在所考虑的时间段内，402名接受监测的患者中有129人接受了至少一种抗癫痫治疗。因此，AEDs的使用患病率为32%。加巴喷丁被发现是最常开具的药物，频率为29%，主要用于治疗焦虑症、精神病、神经性疼痛和情绪障碍。
