Wolf Elizabeth, Rowhani-Rahbar Ali, Tasslimi Azadeh, Matheson Jasmine, DeBolt Chas
Department of Pediatrics and Seattle Children's Research Institute, Seattle, Washington; Department of Pediatrics, Virginia Commonwealth University, Richmond, Virginia; and
Seattle Children's Research Institute, Seattle, Washington; Department of Epidemiology, University of Washington, Seattle, Washington;
Pediatrics. 2016 Jul;138(1). doi: 10.1542/peds.2015-4544.
Underimmunization of certain immigrant populations can place them at high risk of experiencing vaccine-preventable disease outbreaks.
We conducted a retrospective cohort study between January 1, 2008, and May 1, 2013, among children included in the Washington State Immunization Information System. We assessed receipt of 1 or more doses of measles-containing, hepatitis A, pneumococcal, and diphtheria-tetanus-acellular pertussis-containing vaccines between 12 and 23 months of age. We compared children with 1 or more parents born in Somalia, Ukraine, Russia, Mexico, or India to children with 2 parents born in the United States. Poisson regression models with robust SEs were used to provide prevalence ratios adjusted for maternal education and number of prenatal visits.
We identified 277 098 children, including 65 466 with foreign-born parents. Children of Somali-born parents were less likely to be immunized against measles than children of US-born parents (prevalence ratio: 0.82; 95% confidence interval: 0.80-0.84); this decrease became more pronounced over time (P < .01). No such disparity between these groups was observed with other vaccines. Compared with children of US-born parents, children of Ukrainian-born and Russian-born parents were less likely to be immunized, whereas children of Mexican-born and Indian-born parents were more likely to be immunized with any of the specified vaccines.
We found country-specific patterns of immunization that may reflect underlying cultural or other beliefs. Certain immigrant communities with higher rates of immunization refusal may be at risk for vaccine-preventable diseases and require new forms of public health outreach.
某些移民群体疫苗接种不足会使他们面临疫苗可预防疾病暴发的高风险。
我们于2008年1月1日至2013年5月1日在华盛顿州免疫信息系统纳入的儿童中开展了一项回顾性队列研究。我们评估了12至23月龄儿童接种1剂或更多剂含麻疹疫苗、甲型肝炎疫苗、肺炎球菌疫苗和含白喉-破伤风-无细胞百日咳疫苗的情况。我们将父母一方或双方出生于索马里、乌克兰、俄罗斯、墨西哥或印度的儿童与父母双方均出生于美国的儿童进行了比较。采用具有稳健标准误的泊松回归模型来提供经孕产妇教育程度和产前检查次数调整后的患病率比。
我们确定了277098名儿童,其中65466名儿童的父母为外国出生。出生于索马里的父母的子女接种麻疹疫苗的可能性低于出生于美国的父母的子女(患病率比:0.82;95%置信区间:0.80-0.84);随着时间推移,这种差异变得更加明显(P<0.01)。在其他疫苗方面,未观察到这些群体之间存在此类差异。与出生于美国的父母的子女相比,出生于乌克兰和俄罗斯的父母的子女接种疫苗的可能性较小,而出生于墨西哥和印度的父母的子女接种任何一种指定疫苗的可能性较大。
我们发现了特定国家的免疫模式,这可能反映了潜在的文化或其他信念。某些拒绝接种疫苗率较高的移民社区可能面临疫苗可预防疾病风险,需要新形式的公共卫生宣传。