内罗毕河流域幽门螺杆菌与粪便细菌的共存：对公共卫生的影响
Co-occurrence of Helicobacter pylori with faecal bacteria in Nairobi river basin: public health implications.
作者信息
Dinda Victor, Kimang'a Andrew
机构信息
Masinde Muliro University of Science and Technology, Medical Laboratory Sciences.
Jomo Kenyatta Universty of Agriculture & Technology, Medical Microbiology.
出版信息
Afr Health Sci. 2016 Mar;16(1):177-82. doi: 10.4314/ahs.v16i1.24.
INTRODUCTION
Overwhelming evidence implicates Helicobacter pylori (H. pylori) as an etiologic agent of gastrointestinal diseases including gastric cancer. The mode of transmission of this pathogen remains poorly understood.
OBJECTIVE
This investigation is to establish the presence of H. pylori in the waters of the Nairobi river basin and the predictive value the presence of fecal indicator bacteria would have for H. pylori.
METHODOLOGY
Physical, chemical and biological assessment of water quality of rivers in Nairobi were carried out using standard methods. H. pylori DNA in water was detected using highly specific primers of glmM gene (294pb).
RESULTS
There was high presence of faecal bacteria in the waters sampled. H. pylori DNA was detected in two domestic wells and one river. The wells were located in two different regions of the water basin but influenced by similar human activities.
CONCLUSION
The high presence of faecal bacteria in the waters sampled did not parallel the H. pylori detection in the same waters. H. pylori was detected in the Nairobi river basin, but there was no relationship between the numerical levels of fecal bacteria and H. pylori.
引言
大量证据表明，幽门螺杆菌（H. pylori）是包括胃癌在内的胃肠道疾病的病原体。这种病原体的传播方式仍知之甚少。
目的
本研究旨在确定内罗毕河流域水体中幽门螺杆菌的存在情况，以及粪便指示菌的存在对幽门螺杆菌的预测价值。
方法
采用标准方法对内罗毕河流的水质进行物理、化学和生物学评估。使用glmM基因（294pb）的高度特异性引物检测水中的幽门螺杆菌DNA。
结果
所采水样中粪便细菌含量很高。在两口家用井和一条河流中检测到了幽门螺杆菌DNA。这些井位于流域的两个不同区域，但受到类似人类活动的影响。
结论
所采水样中粪便细菌的高含量与同一水体中幽门螺杆菌的检测结果并不平行。在内罗毕河流域检测到了幽门螺杆菌，但粪便细菌的数量水平与幽门螺杆菌之间没有关系。
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