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撒哈拉以南非洲地区胸部诊所中影响哮喘控制治疗依从性因素的评估:一项横断面研究。

Evaluation of factors affecting adherence to asthma controller therapy in chest clinics in a sub-Saharan African setting: a cross-sectional study.

作者信息

Ngahane Bertrand Hugo Mbatchou, Pefura-Yone Eric Walter, Mama Maïmouna, Tengang Bruno, Nganda Motto Malea, Wandji Adeline, Olinga Ubald, Nyankiyé Emmanuel, Afane Ze Emmanuel, Kuaban Christopher

机构信息

Department of Internal Medicine, Douala General Hospital, Douala, Cameroon; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon.

Yaounde Jamot Hospital, Pneumology service, Yaounde, Cameroon; Faculty of Medicine and Biomedical Sciences, Internal medicine and specialities, University of Yaounde I, Yaounde, Cameroon.

出版信息

Afr Health Sci. 2016 Mar;16(1):194-200. doi: 10.4314/ahs.v16i1.26.

Abstract

BACKGROUND

Adherence to controller therapy in asthma is a major concern during the management of the disease.

OBJECTIVE

To determine the adherence rate and identify the predictors of low adherence to asthma controller therapy.

METHODS

A cross-sectional study including asthma patients was conducted from November 1, 2012 to May 31, 2013 in 4 chest clinics in Cameroon. The adherence to asthma treatment was rated using Morisky Medication Adherence Scale. A multivariate logistic regression analysis was performed for the identification of factors associated with adherence to asthma treatment.

RESULTS

Among the 201 asthma patients included, 133 (66.2%) were female. The mean age of participants was 41.2 years. Sixty-one (30.3%) of the patients did not visit the chest physician during the last year prior to the study. Asthma was well controlled in 118 patients (58.7%). The prevalence of low adherence rate to asthma controller therapy was 44.8% and the absence of any chest specialist visit within the last 12 months was the only factor associated with the low adherence rate to asthma treatment (OR 5.57 ; 95% CI 2.84-10.93).

CONCLUSION

The adherence rate to asthma controller therapy in Cameroon is low and it could be improved if scheduled visits are respected by patients.

摘要

背景

在哮喘疾病管理过程中,坚持使用控制药物治疗是一个主要问题。

目的

确定哮喘控制药物治疗的依从率,并找出低依从性的预测因素。

方法

2012年11月1日至2013年5月31日在喀麦隆的4家胸部诊所对哮喘患者进行了一项横断面研究。使用Morisky药物依从性量表对哮喘治疗的依从性进行评分。进行多因素逻辑回归分析以确定与哮喘治疗依从性相关的因素。

结果

纳入的201例哮喘患者中,133例(66.2%)为女性。参与者的平均年龄为41.2岁。在研究前的最后一年中,61例(30.3%)患者未就诊于胸部科医生。118例患者(58.7%)的哮喘得到良好控制。哮喘控制药物治疗的低依从率患病率为44.8%,过去12个月内未就诊于任何胸部专科医生是与哮喘治疗低依从率相关的唯一因素(比值比5.57;95%可信区间2.84 - 10.93)。

结论

喀麦隆哮喘控制药物治疗的依从率较低,如果患者遵守定期就诊安排,依从率可能会提高。

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